Results 181 to 190 of about 34,033 (216)

Establishing efficient multi-gene editing tools for papaya. [PDF]

open access: yesHortic Res
Wang B   +7 more
europepmc   +1 more source

Phase IIB, Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial of Intravenous Defibrotide for the Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome in COVID‐19

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio   +38 more
wiley   +1 more source

Combining polygenic risk scores to understand genetic liability to physical-mental health multimorbidity in UK Biobank. [PDF]

open access: yesHum Mol Genet
Stow D   +10 more
europepmc   +1 more source

Spinoza on Humans as Social Animals

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract Spinoza repeatedly suggests that humans are set apart from other animals by their rational and moral abilities. Yet he disparages the traditional definition of the human as a ‘rational animal’ and several of his other views suggest that these abilities are not sufficient by themselves to characterize human nature.
Ruben Noorloos
wiley   +1 more source

Cryo‐EM structure of GH43 β‐Xylosidase from Enterobacter cloacae provides insights into substrate specificity and the role of an auxiliary domain in enzymatic activity

open access: yesThe FEBS Journal, EarlyView.
Xylan, the second most abundant plant cell wall polysaccharide, is degraded by β‐xylanases and β‐xylosidases. Here, we present the 2.65 Å cryo‐EM structure of Enterobacter cloacae β‐xylosidase (EcXyl43, GH43) and the 2.4 Å X‐ray structure of its inactive F507A mutant.
Lorenzo Briganti   +8 more
wiley   +1 more source

Reimagining Trust as Feminist Praxis: A Transnational Analysis of Gender and Public Confidence in Women's Organizations

open access: yesGender, Work &Organization, EarlyView.
ABSTRACT This paper examines trust in women's organizations as a gendered and contextually embedded dimension of institutional trust, drawing on data from 90,192 respondents across 60 countries using the 2017–2022 World Values Survey, the World Bank, and Varieties of Democracy.
Ruby Amanda Oboro‐Offerie
wiley   +1 more source

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