Results 41 to 50 of about 5,174,614 (290)
The risk model with stochastic premiums, dependence and a threshold dividend strategy
Modern Stochastics: Theory and Applications, 2017 The paper deals with a generalization of the risk model with stochastic premiums where dependence structures between claim sizes and inter-claim times as well as premium sizes and inter-premium times are modeled by Farlie–Gumbel–Morgenstern copulas.
Olena Ragulina
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
On a generalization of the expected discounted penalty function to include deficits at and beyond ruin [PDF]
European Actuarial Journal, 2014 In this chapter we propose an extended concept of the expected discounted penalty function (EDPF) that takes into account new ruin-related random variables. We add to the EDPF, which was introduced in classical papers [Gerber and Shiu (1997), (1998) and Gerber and Landry (1998)], a sequence of expected discounted functions of new record minima reached ...
openaire +3 more sources
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Some optimization and decision problems in proportional reinsurance
Rect@, 2016 Reinsurance is one of the tools that an insurer can use to mitigate the underwriting risk and then to control its solvency. In this paper, we focus on the proportional reinsurance arrangements and we examine several optimization and decision problems of ...
Castañer, Anna +2 more
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Ruin Probability Analysis in Automobile Insurance Using Gamma-Cubic Transmuted Exponential Distribution for Claim Severity [PDF]
International Journal of Mathematical, Engineering and Management SciencesInsurance companies must confront and manage financial risks to ensure their survival. This article analyzes and manages risks by estimating ruin probability using the newly developed Gamma-Cubic Transmuted Exponential (GCTE) claim severity distribution.
Jiramet Hengcharoensuk, Adisak Moumeesri
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Optimal Dividends for a Two-Dimensional Risk Model with Simultaneous Ruin of Both Branches
Risks, 2022 We consider the optimal dividend problem in the so-called degenerate bivariate risk model under the assumption that the surplus of one branch may become negative.
Philipp Lukas Strietzel +1 more
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FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
The tourism function of the castles of the Knights of the Teutonic Order in Poland
Tourism, 2014 The author’s main objective is to define the level of development of the tourism function of the Teutonic Order castles found in the area of contemporary Poland.
Łukasz Musiaka
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