Results 231 to 240 of about 3,572 (307)

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

Emerging, challenges and modernization path of gene privacy in China: from personal privacy to group privacy. [PDF]

Philos Ethics Humanit Med
Chen J, Li W.
europepmc   +1 more source

Regulation and Ruin Theory

, 2007
Guillaume Plantin, Jean‐Charles Rochet
openalex   +1 more source

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

Advanced Science, EarlyView.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha, Benjamin Yang, Dongqiang Yuan, Edmund D. Kapelczak, Philip A. Kocheril, Alonso Tapia, Shivansh Mahajan, Adrian Colazo, Naseeb K. Malhi, Joseph A. Ambarian, Xuejing Liu, Tara A. TeSlaa, Zhen B. Chen, Lu Wei   +13 more
wiley   +1 more source

Living well? The unintended consequences of highly popular commercial fitness apps through social listening using Machine-Assisted Topic Analysis: Evidence from X. [PDF]

Br J Health Psychol
Sheen F, Porter L, Papakonstantinou T, Ceka M, Bondaronek P.   +4 more
europepmc   +1 more source

A Methodology for Deciphering the Transmembrane Resistance Variability of Supported Lipid Bilayers

Advanced Science, EarlyView.
This work shows that transmembrane resistance variability, due to lipid packing defects, can be quantified by analysing the dielectric properties of Supported Lipid Bilayers. The proposed methodology provides an analytical tool for optimizing SLB design with improved stability and functionality for bioelectronic and biomimetic applications. Abstract In
Aristea Pavlou, Debdatta Panigrahi, Somayeh Kashani, Anna‐Maria Pappa, Fabrizio Torricelli, Paul W.M. Blom, Paschalis Gkoupidenis   +6 more
wiley   +1 more source

Validating Community for Successful Ageing (ComSA) BioPsychoSocial Risk Screener Version II (BPS-RS II) with Diverse Multi-Ethnic Senior Populations in Singapore: A Mixed-Methods Study. [PDF]

BMC Geriatr
Aw S, Shiraz F, Vrijhoef HJM, Jiajing KX, Yin JD, Ng WC, Lim ZZB, Keong POC, Koh GCH, Hildon ZJ.   +9 more
europepmc   +1 more source

The effect of goal frame and risk perception on digital flood prevention tool acceptability. [PDF]

Front Psychol
Jezierski T, Ragot-Court I, Weiss K.
europepmc   +1 more source

Methylphenidate in Post-Stroke Rehabilitation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Cureus
Sathyanarayanan A, Vummiti S, Pudukayil Pudiyamaliyakkal A.   +2 more
europepmc   +1 more source