Results 61 to 70 of about 849,237 (330)
On ruin probabilities with risky investments [PDF]
arXiv, 2020 We investigate the asymptotic of ruin probabilities when the company combines the life- and non-life insurance businesses and invests its reserve into a risky asset with stochastic volatility and drift driven by a two-state Markov process. Using the technique of the implicit renewal theory we obtain the rate of convergence to zero of the ruin ...
arxiv
Interplay of integrins and selectins in metastasis
Molecular Oncology, EarlyView.Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva +2 more
wiley +1 more source
Optimal policies for discrete time risk processes with a Markov chain investment model [PDF]
, 2006 We consider a discrete risk process modelled by a Markov Decision Process. The surplus could be invested in stock market assets. We adopt a realistic point of view and we let the investment return process to be statistically dependent over time.
Diasparra, Maikol, Romera, Rosario
core +1 more source
From ruin to bankruptcy for compound Poisson surplus processes [PDF]
, 2013 In classical risk theory, the infinite-time ruin probability of a surplus process Ct is calculated as the probability of the process becoming negative at some point in time.
Albrecher, H., Lautscham, V.
core +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Parisian excursion with capital injection for draw-down reflected Levy insurance risk process [PDF]
arXiv, 2020 This paper discusses Parisian ruin problem with capital injection for Levy insurance risk process. Capital injection takes place at the draw-down time of the surplus process when it drops below a pre-specified function of its last record maximum. The capital is continuously paid to keep the surplus above the draw-down level until either the surplus ...
arxiv
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Randomized observation times for the compound Poisson risk model: The discounted penalty function [PDF]
, 2013 In the framework of collective risk theory, we consider a compound Poisson risk model for the surplus process where the process (and hence ruin) can only be observed at random observation times. For Erlang(n) distributed inter-observation times, explicit
Albrecher, H. +2 more
core +2 more sources
Social Sciences and Humanities Open, 2022 Business and Psychology research (and the Social Sciences, in general) is heavily biased toward explaining the past. The holy grail in such explanation-oriented research is to develop causal theory, and to test this theory with historical data against a ...
Arjen van Witteloostuijn +5 more
doaj
Crime Against History: Slavery, Race, and the 1776 Report
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT With the 2025 executive order, “Ending Radical Indoctrination in K‐12 Schooling,” the Trump administration reestablished the 1776 Commission, which produced The 1776 Report. This article argues that this report, which is an unsubtle response to The 1619 Project, reveals how White Christian Nationalists wish to mandate that a hyper‐patriotic ...
William V. Trollinger
wiley +1 more source