Results 231 to 240 of about 2,970,912 (342)

Rules railroad: Syntax-inspired diagrams for visualizing and understanding rule-based model specifications. [PDF]

PLoS Comput Biol
Patel RJ, Blinov ML.
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Spatiotemporal characterisation of information coding in the multiple demand network. [PDF]

Imaging Neurosci (Camb)
Karimi-Rouzbahani H, Rich AN, Woolgar A.
europepmc   +1 more source

Comparative Analysis of Rule-Based and Model Predictive Control Algorithms in Reconfigurable Battery Systems for Ev Fast-Charging Stations

Zoltan Mark Pinter, Gunnar Rohde, Mattia Marinelli   +2 more
openalex   +1 more source

Application of Rule Based Control to Flow Line Control

Transactions of the Society of Instrument and Control Engineers, 1985
Isao TSUSHIMA, Tsutomu TASHIRO, Norihisa KOMODA, Kazushi BABA, Syuuichi TAKAKURA   +4 more
openaire   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Modeling metacognition and executive functions in the metacognitive wisconsin card sorting test using the neuropsychological digital-twin method. [PDF]

Sci Rep
Granato G, Mattera A, Cartoni E, Baldassarre G.   +3 more
europepmc   +1 more source

Extended data for: Improving Medication Safety in Chronic Kidney Disease Using Rule-Based and Artificial Intelligence–Based Clinical Decision Support Systems: A Systematic Review of Randomized Controlled Trials

Asrul Ismail, Rani Sauriasari, Arry Yanuar, Dodi Sudiana, Fonny Cokro   +4 more
openalex   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Impact of Proton Therapy Implementation on Processes, Patient Satisfaction, and Technology Use in a Radiation Therapy Department. [PDF]

Adv Radiat Oncol
Heising L, Ackermans T, Boersma L, Ou C, Bosmans G, Swart R, Dekker A, Jacobs M.   +7 more
europepmc   +1 more source