Results 271 to 280 of about 2,970,912 (342)

PM-QCIS: A Rule-Based Clinical Laboratory Quality Control Intelligence System for Sigma-Driven Analytical Decision Support

Prasenjit Mitra
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Functional connectivity-based attractor dynamics of the human brain in rest, task, and disease. [PDF]

Elife
Englert R, Kincses B, Kotikalapudi R, Gallitto G, Li J, Hoffschlag K, Woo CW, Wager TD, Timmann D, Bingel U, Spisak T.   +10 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Unlocking predictive genetic factors with artificial intelligence: relationship between dental impaction and hypodontia evaluated via association-rule algorithms: a case-control study. [PDF]

Saudi Dent J
Alhazmi N, Alaqla A, Almuzzaini B, Aldrees M, Alnaqa G, Almasoud F, Thomas SK, Alshamlan H.   +7 more
europepmc   +1 more source

Adaptive control of electromagnetic suspension based on reinforcement learning and fuzzy rules

Zefeng Ding, Haili Tang, Xiaojuan Cao
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Design of a parameter self-tuning PID controller based on an ER-SLP for a variable-frequency air compressor in a rapid deballasting system. [PDF]

Sci Rep
Pang S, Zhou J.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Mitigating Neural Habituation in Insect Bio-Bots: A Dual-Timescale Adaptive Control Approach. [PDF]

Biomimetics (Basel)
Triet LM, Truong Thinh N.
europepmc   +1 more source