Results 61 to 70 of about 2,970,912 (342)

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Energetic, Cost, and Comfort Performance of a Nearly-Zero Energy Building Including Rule-Based Control of Four Sources of Energy Flexibility

Buildings, 2018
A focal point of ongoing research is matching the energy demand in the built environment to the energy supply from onsite generation, to maximize the self-consumption, and from the energy grids, to lower energy costs and reduce peak loads on the system ...
Benjamin Manrique Delgado, Reino Ruusu, Ala Hasan, Simo Kilpeläinen, Sunliang Cao, Kai Sirén   +5 more
doaj   +1 more source

Trajectory Tracking with Adaptive Robust Control for Quadrotor

Applied Sciences, 2021
This work proposes three robust mechanisms based on the MIT rule and the sliding-mode techniques. These robust mechanisms have to tune the gains of an adaptive Proportional-Derivative controller to steer a quadrotor in a predefined trajectory.
Tadeo Espinoza-Fraire, Armando Saenz, Francisco Salas, Raymundo Juarez, Wojciech Giernacki   +4 more
doaj   +1 more source

How useful are the stages of change for targeting interventions? randomized test of a brief intervention to reduce smoking [PDF]

, 2008
Objectives. To see whether the stages of change are useful for targeting a brief intervention to reduce smoking based on implementation intentions. A second objective was to rule out demand characteristics as an alternative explanation for the findings
Arden, M. A., Armitage, C. J.
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

How a multiple orientation of control reduces governance failures: a focus on monastic auditing [PDF]

, 2014
This paper considers multiple control systems at the organizational level and argues for a nuanced and multifaceted approach for internal governance.
Frey, B.S., Homberg, Fabian, Inauen, E., Osterloh, M.   +3 more
core   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The Impact of Optimal Demand Response Control and Thermal Energy Storage on a District Heating System

Energies, 2019
Demand response has been studied in district heating connected buildings since the rollout of smart, communicating devices has made it cost-effective to control buildings’ energy consumption externally.
Sonja Salo, Aira Hast, Juha Jokisalo, Risto Kosonen, Sanna Syri, Janne Hirvonen, Kristian Martin   +6 more
doaj   +1 more source