Results 181 to 190 of about 166,647,776 (295)

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

open access: yesAdvanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer   +12 more
wiley   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave   +8 more
wiley   +1 more source

Why the Rule of Law Matters for Nonprofits [PDF]

open access: yes
The Rule of Law is what keeps tax exemption from being a political weapon and allows for nonprofit organizations to provide services the government is not providing our ...
University of Washington School of Law
core  

Multiwavelength Implantable Oximeter for Wireless Monitoring of Tissue Oxygenation in the Presence of Blood Volume Changes

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents an implantable, wireless, battery‐free oximeter that can continuously monitor physiologically consistent regional tissue oxygenation under dynamic changes of blood volume. This is achieved through multiwavelength photoplethysmography and validated both via Monte Carlo simulations and in vivo rat studies. Different stress events were
Anat Usatinsky   +12 more
wiley   +1 more source

Silicone Breast Implants as a Model System for Understanding Polymer Permeation in Soft Materials In Vivo

open access: yesAdvanced Healthcare Materials, EarlyView.
Silicone breast implants are presented as a model system for understanding polymer permeation in vivo. Rather than representing material failure, “gel bleed” emerges from solution–diffusion transport‐mediated. By integrating polymer architecture, physicochemical transport, and biointerfacial processes, this review provides a unified framework that ...
D. Bouyer   +12 more
wiley   +1 more source

Plasma Gelation as an Overlooked Determinant of Transfection Efficiency in Protein Corona‐Coated Lipid Nanoparticles: Implications for In Vitro–In Vivo Translation

open access: yesAdvanced Healthcare Materials, EarlyView.
Upon contact with plasma, lipid nanoparticles (LNPs) rapidly acquire a protein corona (PC) that redefines their biological identity. In calcium‐containing environments, these coronated particles trigger the formation of a gel‐like plasma network, profoundly altering their transport properties and reducing their effective availability.
Serena Renzi   +14 more
wiley   +1 more source

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