Results 21 to 30 of about 118,218 (259)

Does Digitalization Reshape the Principle of Non-Intervention?

German Law Journal, 2023
While digitalization has led to renewed attention to the principle of non-intervention, not the least by Western states rediscovering the protective dimension of sovereignty, it remains plagued by a certain vagueness.
Lukas Willmer
doaj   +1 more source

Russian Financial Statements Database: A firm-level collection of the universe of financial statements

Scientific Data
The Russian Financial Statements Database (RFSD) is an open, harmonized collection of annual unconsolidated financial statements of the universe of Russian firms in 2011–2023.
Sergey Bondarkov, Viktor Ledenev, Dmitry Skougarevskiy   +2 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Exploring Linkages Between Rule of Law Backsliding and Human Rights: How to Find the Brakes on a Slippery Slope?

Utrecht Law Review
Backsliding is a global phenomenon that does not only occur in terms of the level or quality of democracy. It also can be traced in an, often deliberate, weakening of the rule of law and a connected deterioration of human rights protection. We argue that
Hadeel S. Abu Hussein, Antoine Buyse, Katharine Fortin   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

‘Global law’ and governmentality: Reconceptualizing the ‘rule of law’ as rule ‘through’ law [PDF]

European Journal of International Relations, 2010
This article challenges the optimism common to liberal IR and IL scholarship on the ‘rule of law’ in global governance. It argues that the concept of the ‘rule of law’ is often employed with sparse inquiry into the politics of its practical meaning.
openaire   +3 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

رد الاعتبار القانوني وأثره تجاه حق النزلاء المفرج عنهم في العمل وإعادة الإدماج في المجتمع

Malaysian Journal of Syariah and Law, 2020
تضمنت هذه الدراسة التعريف بمفهوم رد الاعتبار في القوانين الوضعية والشريعة الإسلامية، وما يترتب على الممارسات القانونية الحالية من إشكالية في حرمان من يرتكب جريمة من وثيقة عدم المحكومية التي تصدر بموجب رد الاعتبار، والأساس الحقوقي الذي يتعارض فيما بين ...
abdallah suleiman Abuzaid, Hasnizam Hashim, Norman Zakiyy Chow Jen T’Chiang   +2 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source