Results 31 to 40 of about 3,874,998 (408)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Bilateral Rules as Complex Rules

open access: yesBulletin of the Section of Logic, 2023
Proof-theoretic semantics is an inferentialist theory of meaning originally developed in a unilateral framework. Its extension to bilateral systems opens both opportunities and problems. The problems are caused especially by Coordination Principles (a kind of rule that is not present in unilateral systems) and mismatches between rules for assertion and
openaire   +2 more sources

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker   +11 more
wiley   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

RULES OF COURT [PDF]

open access: yes, 2008
In accordance with the African Charter on Human and Peoples' Rights of 27 June 1981 and the Protocol thereof on the Establishment of an African Court on Human and Peoples’ Rights dated 9 June 1998, And in pursuance of article 33 of the Protocol, Adopts ...
African Union
core  

Research on Weak Magnetic Control of IPMSM with Single Current Regulator Based on Improved Terminal Sliding Mode

open access: yes水下无人系统学报
In view of the poor stability of permanent magnet motors in undersea vehicle propulsion systems under deep weak magnetic conditions, a weak magnetic control method with a single current regulator was proposed for the interior permanent magnet synchronous
Shaowei GAN   +4 more
doaj   +1 more source

Rules, Games, and Common-Pool Resources

open access: yes, 1994
While the tragedy of the commons is real, there are many instances where institutions develop to protect against overexploitation. In this important work, the authors explore empirically, theoretically, and experimentally the nature of such institutions ...
E. Ostrom, R. Gardner, James M. Walker
semanticscholar   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Rules of Court [PDF]

open access: yes, 2010
Rules of ...
ACHPR
core  

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