Results 71 to 80 of about 3,874,998 (408)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Committee report on senate rules

open access: yes, 1945
Title from PDF caption (viewed on March 6, 2017).This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program.

core  

The End of Doctrine?<br>On the Symbolic Function of Doctrine in Substantive Criminal Law

open access: yesUtrecht Law Review, 2011
Recently, there have been various developments within Dutch substantive criminal-law doctrine that in some important ways suggest a shift towards a common-law conception of judicial interpretation in different topics which are central to substantive ...
Ferry de Jong
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Guide to filing Oregon administrative rules

open access: yes, 1995
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes."August 1995."Title from coverMode of access: Internet from ...

core  

Automatic Generation of Figural Analogies With the IMak Package

open access: yesFrontiers in Psychology, 2018
Automatic Item Generation (AIG) techniques are offering innovative ways to produce test items as they overcome many disadvantages involving standard item writing, such as time-consuming work and resource-intensive demands.
Diego Blum, Heinz Holling
doaj   +1 more source

From rules to rule patterns [PDF]

open access: yes, 1996
Rule-based systems are a commonly accepted solution for smoothly capturing the context-dependent and time-dependent organizational knowledge of large enterprises, also known as business policies. At the same time, however, the design of rule-based applications is one of the most pressing open research problems. This is largely because of the expressive
Gerti Kappel   +3 more
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Ce ție nu-ți place altuia nu-i face: Despre regula de aur în pandemie [PDF]

open access: yesForum Juridic, 2020
The paper develops on John Rawls ‘golden rule’ and applies it to the current pandemic situation. In doing so, it starts with the presentation of a trivia case to illustrate the double standard we tend to apply when it comes to our actions as compared to ...
Radu Rizoiu
doaj  

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