Results 221 to 230 of about 422,202 (345)

Multicentre quality improvement initiative to improve patient education and safety in the prescription of Sodium-Glucose transporter 2 inhibitors. [PDF]

BMJ Open Qual
Saad L, Adiga A, Anwar Mohamed M, Saha P, Kuehl M, Banerjee P, Tran P.   +6 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Rural-Urban Patterns in Household Rules Limiting Combustible Tobacco, Noncombustible Tobacco, and E-Cigarette Use. [PDF]

Ann Am Thorac Soc
Steinberg AW, Ozga JE, Tang Z, Stanton CA, Sargent JD, Paulin LM.   +5 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Indiana's Patterson Rule of Evidence: Its Evolution, Misapplication, and Correction

, 2011
Terry L. Zabel
openalex   +1 more source

Application and clinical utility assessment of natural language processing-based software for copy-number variants interpretation. [PDF]

J Transl Med
Chen S, Liu C, Luan X, Wang Y, Xu Y, Li Y, Zhang F, Shi W, Zhou X, Xu C.   +9 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Do Selection Rules A ect Leader Responsiveness? Evidence from Rural Uganda

, 2013
Guy Grossman
openalex   +1 more source

Nursing Performance Using Clinical Prediction Rules for Acute Respiratory Infection Management: A Case-Based Simulation. [PDF]

Appl Clin Inform
Tiase VL, Hicks P, Bah H, Snow A, Mann DM, Feldstein DA, Halm W, Smith PD, Hess R.   +8 more
europepmc   +1 more source

The Certainty of evidence rules and the admissibility of evidence

CHUNG_ANG LAW REVIEW, 2011
openaire   +1 more source