Results 51 to 60 of about 422,202 (345)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Elements concerning sanctions in the rules criminalizing the falsification of evidence [PDF]

open access: yesRevista Institutului Naţional de Justiţie, 2019
In this article, the author carried out extensive and detailed investigations into other countries’ criminal matters to identify legal norms that criminalize responsibility for facts that affect social relationships about the authenticity of evidence in ...
Gherman Marin, Piterschi Eugeniu
doaj  

Adillatu al-Nahw Fi Syarh Kitab al-Kawakib al-Durriyyah 'Ala Mutammamah al-Ajrumiyah wa Atsar Isti'maluha 'Ala Fahm al-Qowaid al-Nahwiyah

open access: yesArabiyatuna: Jurnal Bahasa Arab, 2019
The objectives of this study were to find out the syntax evidence (adillah al-nahwu) in the book Syarh Kitab al-Kawakib al-durriyah ‘ala Mutamammimah al-Ajrumiyyah, how to use the evidence of syntax (adillah al-nahwu) in it’s book, and what are the ...
Asrina Asrina, Arbonas Lubis
doaj   +1 more source

Tips for Teachers of Evidence-based Medicine: Clinical Prediction Rules (CPRs) and Estimating Pretest Probability

open access: yesJournal of general internal medicine, 2008
BackgroundClinical prediction rules (CPR) are tools that clinicians can use to predict the most likely diagnosis, prognosis, or response to treatment in a patient based on individual characteristics.
T. McGinn   +4 more
semanticscholar   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Em defesa do Direito Probatório fundado em regras - e da Epistemologia também

open access: yesTeoria Jurídica Contemporânea, 2017
RESUMO: Desde que Jeremy Bentham escreveu a sua severa crítca ao Direito Probatório, filósofos e juristas têm critcado as regras probatórias excludentes argumentando que as regras formais que excluem classes inteiras de provas em razão da sua alegada ...
Frederick Schauer
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Balanced Budget Rules and Fiscal Outcomes: Evidence from Historical Constitutions

open access: yesJournal of Public Economics, 2016
This paper studies the long-run fiscal consequences of balanced budget rules (BBR) that are enshrined in a country's constitution. Using historical data dating back to the 19th century and applying a difference-in-difference approach we find that the ...
Zareh Asatryan   +2 more
semanticscholar   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Overriding Mandatory Rules Applicable to International Sales of Goods: Evidence from South Africa

open access: yesLex Portus, 2023
In private international law of contract, the law regulating the rights and obligations of contracting parties may (whether objectively determined or chosen by the parties), in some instances, be limited by either public policy considerations or other ...
Prince Obiri-Korang
doaj   +1 more source

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