Results 71 to 80 of about 422,202 (345)

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

The Contribution of the Prague Rules to Promoting Efficiency in International Arbitration

open access: yesThēmis, 2020
The Prague Rules are intended to provide efficiency and reduce costs in conducting arbitration proceedings. The Rules are based on the position that the practice and procedure of international arbitration is too heavily influenced by the adversarial ...
Gisèle Stephens-Chu, Camille Teynier
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

How to dissect the pelvic nerves: from microanatomy to surgical rules. An evidence-based clinical review. [PDF]

open access: yesFacts Views Vis Obgyn, 2022
Aleksandrov A   +3 more
europepmc   +1 more source

Modularity Design Rules for Architecture Development: Theory, Implementation, and Evidence from the Development of the Renault–Nissan Alliance “Common Module Family” Architecture

open access: yesJournal of Open Innovation: Technology, Market and Complexity, 2018
In this paper, we propose a set of rules for developing modular architectures. We first consider the well-known concept of “Design Rules” advanced by Baldwin and Clark.
R. Sanchez, T. Shibata
semanticscholar   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Leveraging AI-Evidence in Money Laundering Cases in Mexico: its Rules of Evidence (according to SCJN’s resolutions)

open access: yesRevista de Direito, Estado e Telecomunicações
[Purpose] To analyzethe admissibility of AI-generated evidence in money laundering cases in Mexico, with an emphasis on how this type ofevidence might be evaluated underexisting SCJNresolutions.[Methodology/approach/design]Thisresearchusesa ...
Patricia Margarita Sanchez Reyes
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Copyright as a Rule of Evidence [PDF]

open access: yesSSRN Electronic Journal, 2002
This Article endeavors to offer a unified explanation for a wide variety of copyright doctrines, including the fixation requirement, the merger doctrine and the requirement that eligible works demonstrate at least a modicum of creativity. That explanation: these doctrines mitigate what would otherwise be difficult problems of proof.
openaire   +6 more sources

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