Results 91 to 100 of about 1,252,805 (288)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Run - Up dan Run - Down Akibat Pengaruh Sudut Datang Gelombang pada Berbagai Unit Lapis Lindung Pemecah Gelombang

open access: yesJurnal Teknik Sipil, 2010
Abstrak. Beberapa variabel yang mempengaruhi untuk perencanaan struktur pemecah gelombang adalah tinggi run-up and run-down. Gelombang run-up dapat digunakan sebagai variable untuk menentukan struktur pantai dan gelombang run-down untuk kerusakan ...
Sriyana Sriyana   +2 more
doaj  

Interbank network and bank bailouts: Insurance mechanism for non-insured creditors? : [Version 20 Februar 2013] [PDF]

open access: yes, 2013
This paper presents a theory that explains why it is beneficial for banks to engage in circular lending activities on the interbank market. Using a simple network structure, it shows that if there is a non-zero bailout probability, banks can ...
Eisert, Tim, Eufinger, Christian
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

KAJIAN STABILITAS COUNTERFORT WALL PADA ESCAPE HILL TERHADAP FREEBOARD DAN RUN UP LEVEL

open access: yesTeras Jurnal: Jurnal Teknik Sipil, 2019
Mengingat berbagai ancaman gempa yang menimbulkan tsunami dan masih kurangnya upaya yang optimal dalam pembangunan tempat evakuasi maka perlu dilakukan kajian-kajian terhadap tempat evakuasi sementara yaitu bukit buatan (escape hill).
Tasia Oktanuansania Tasia Oktanuansania
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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