Results 81 to 90 of about 13,068 (272)

Mixed‐mode membrane chromatography: mechanistic‐modeling‐based optimization and scale‐up of antibody charge variant separation using a novel membrane adsorber

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Efficient manufacturing of complex biopharmaceuticals increasingly relies on innovative downstream processing strategies. Membrane chromatography offers a promising alternative to resin‐based systems by enabling high‐throughput separations at elevated flow rates. Typically used in flow‐through mode, its industrial applications range
Jan Hedrich, Rita Steigmiller, Viktor Simaev, Romas Skudas, Michael Schulte, Mathias Hafner, Christian Frech   +6 more
wiley   +1 more source

Investigating Tuberculosis Dynamics Under Various Control Strategies: A Comprehensive Analysis Using Real Statistical Data

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In the present investigation, a mathematical model with vaccination, treatment, and environmental impact under real data is presented. Initially, we present the model without any interventions, followed by an examination of its equilibrium points.
Bashir Al‐Hdaibat, Mahmoud H. DarAssi, Irfan Ahmad, Muhammad Altaf Khan, Reem Algethamie   +4 more
wiley   +1 more source

Impulsive Discrete Runge–Kutta Methods and Impulsive Continuous Runge–Kutta Methods for Nonlinear Differential Equations with Delayed Impulses

Mathematics
In this paper, we study the asymptotical stability of the exact solutions of nonlinear impulsive differential equations with the Lipschitz continuous function f(t,x) for the dynamic system and for the impulsive term Lipschitz continuous delayed functions
Gui-Lai Zhang, Zhi-Yong Zhu, Yu-Chen Wang, Chao Liu   +3 more
doaj   +1 more source

Analytical Solutions for the Cardiac Extracellular‐Membrane‐Intracellular Model

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT The cardiac extracellular‐membrane‐intracellular (EMI) model is a novel mathematical framework for cardiac electrophysiology simulations. The cardiac EMI model provides a more detailed description of the heart's electrical activity compared to traditional monodomain and bidomain models, potentially making it better‐suited for understanding the
Carlos Ballesteros, Alexei Cheviakov, Raymond J. Spiteri   +2 more
wiley   +1 more source

Fitted modifications of Runge‐Kutta pairs of orders 6(5)

Mathematical methods in the applied sciences, 2018
Runge‐Kutta (RK) pairs sharing orders 6 and 5 are widely used for solving initial value problems. Thus, we consider the dispersion from a standard cyclic orbit as a function of frequency v and present a modification of a particular pair.
M. Medvedev, T. Simos, C. Tsitouras
semanticscholar   +1 more source

Thermal Planar and Radial Free Jets for An Ostwald‐de Waele Fluid With Shear‐Rate Dependent Thermal Diffusivity

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT The planar and radial thermal free jets for forced convection of a non‐Newtonian power‐law fluid are investigated. The thermal diffusivity is dependent on the shear‐rate and is not a constant. The flow in planar and radial thermal free jets is governed by the momentum, continuity and energy balance equations. In the stream‐function formulation,
Avnish Bhowan Magan, Rehana Naz
wiley   +1 more source

Numerical Investigation of a Diffusive SIR Model: Focus on Positivity Preservation

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In this paper, we consider a system of semilinear partial differential equations (PDEs) representing a spatially extended SIR epidemic model. A brief analytical investigation of the well‐posedness and positivity of the solutions is provided in the appendix, while the main focus is on the numerical treatment of the model.
Rahele Mosleh, Claudia Panico, Messoud Efendiyev   +2 more
wiley   +1 more source

Stability Analysis of Additive Runge-Kutta Methods for Delay-Integro-Differential Equations

International Journal of Differential Equations, 2018
This paper is concerned with stability analysis of additive Runge-Kutta methods for delay-integro-differential equations. We show that if the additive Runge-Kutta methods are algebraically stable, the perturbations of the numerical solutions are ...
Hongyu Qin, Zhiyong Wang, Fumin Zhu, Jinming Wen   +3 more
doaj   +1 more source

Effect of Variations in the Ring Thickness on the Dynamic Performance of the Bimetal Gears

International Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT This study used a six‐degrees‐of‐freedom dynamic model to analyze the dynamic response of bimetal spur gears. Aluminum alloy forms the core of the bimetal gears, and a uniform‐thickness steel ring surrounds the teeth. Gear mesh stiffness of bimetal gears and the transmission error have been assessed using a numerical approach based on finite ...
Bikramjit Singh, Pawan Kumar, S. P. Harsha   +2 more
wiley   +1 more source

Characterization of Fuel Rods Supported by Dimple‐Less Spacer Grids and Subjected to Nonlinear Vibrations

International Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT An experimental campaign was undertaken to demonstrate the applicability of the Bouc–Wen hysteretic model to describe the hysteretic system of the recent Framatome dimple‐less spacer grid design for Pressurized Water Reactors. The experimental setup subjected a reduced‐length fuel rod, supported at both ends by dimple‐less grids, to forced ...
Giovanni Ferrari, Brian Painter, Kostas Karazis, Marco Amabili   +3 more
wiley   +1 more source