Results 91 to 100 of about 750,368 (294)
The running economy difference between running barefoot and running shod [PDF]
Journal of Human Sport and Exercise, 2015 Barefoot (BF) running is very popular topic among runners and coaches, and very often discussed in papers and even mass-media point is health aspect. The aim of this study is verify influence BF on physiological indicators. Nine women (age 21.1 ± 1.79 y.o., weight 59.7 ± 5.86 kg, height 164.8 ± 4.02 cm, no previous BF running experience, athletes, non ...
Kalina, Tomáš +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Theoretical Computer Science, 2011 AbstractThe “runs” conjecture, proposed by Kolpakov and Kucherov (1999) [7], states that the number of occurrences of maximal repetitions (runs) in a string of length n, runs(n), is at most n. We almost solve the conjecture by proving that runs(n)⩽1.029n. This bound is obtained using a combination of theory and computer verification.
Crochemore, Maxime +2 more
openaire +4 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Proceedings of the American Mathematical Society, 1962 According to a theorem of Alfred Brauer [1] all sufficiently large primes have runs of I consecutive integers that are kth power residues, wher-e k and I are arbitrarily given integers. In this paper we consider the question of the first appearance of such runs.
Emma Lehmer, D. H. Lehmer
openaire +2 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Pacing of Women and Men in Half-Marathon and Marathon Races
Medicina, 2019 Background and objective: Half-marathon is the most popular endurance running race in terms of number of races and runners competing annually; however, no study has compared pacing strategies for this race distance with marathon.
Pantelis T. Nikolaidis +2 more
doaj +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source