Results 121 to 130 of about 750,368 (294)

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

The Effect of Five-Toed Shoes on Electromyographic Activity of Leg Muscles During Stance Phase of Running

open access: yesPhysical Treatments, 2017
Purpose: The current study aimed at evaluating the effect of 5-toed shoes on electromyographic activity of leg muscles during the stance phase of running.
Hamideh Khodaveisi   +2 more
doaj  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Local Asymmetry and Global Symmetry During Jogging in Young Male Athletesetes

open access: yesPhysical Treatments, 2018
Purpose: Evaluation of joints behavioral symmetry of the lower limbs to produce a smooth, rhythmic movement is one of the topics in the field of biomechanics of running. This study investigated joints local and global symmetry while jogging in young male
Alireza Nasirzade   +1 more
doaj  

Distribution of round-off errors for running averages [PDF]

open access: bronze, 1953
Robert E. Greenwood, Andrew M. Gleason
openalex   +1 more source

Runs and Integration

open access: yesReal Analysis Exchange, 2005
The author introduces a general notion of the integral by the help of runs. The notion of a run has been defined by \textit{H. Kenyon} and \textit{A. P. Morse} [``Runs'', Pac. J. Math. 8, 811--824 (1958; Zbl 0084.37803)] and it can be considered as an alternative to filters and nets.
openaire   +3 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Coactivation of the Pelvic Floor and Gluteus Medius Muscles While Walking and Running in Female Runners

open access: yesSensors
(1) Background: Pelvic-floor-muscle (PFM) activation acts synergistically with multiple muscles while performing functional actions in humans. The purpose of this study was to characterize the activity of the PFMs and gluteus medius (GM) while walking ...
Avelaine Porrón-Irigaray   +4 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

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