Results 181 to 190 of about 22,226,095 (257)

Lasso for hierarchical polynomial models

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract The divisibility conditions implicit in a polynomial hierarchy suggest parameter constraints in regression. With this idea, we establish strong and weak hierarchies for both the lasso and relaxed lasso. Our proposal extends prior work on hierarchical lasso, which was mainly concerned with models of degree 2.
H. Maruri‐Aguilar, S. Lunagómez
wiley   +1 more source

In Silico Clinical Trials in Drug Development: Virtual Patients, Applications, and Regulatory Convergence

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Conventional clinical trials remain the benchmark for evaluating therapeutic safety and efficacy, yet they are constrained by escalating costs, withdrawal over the extended follow‐up periods, recruitment difficulties, ethical limits, and a restricted ability to characterize heterogeneous populations.
Maximilian Balmus   +7 more
wiley   +1 more source

2D Implementation of Kinetic‐Diffusion Monte Carlo in Eiron

open access: yesContributions to Plasma Physics, EarlyView.
ABSTRACT Particle‐based kinetic Monte Carlo simulations of neutral particles are one of the major computational bottlenecks in tokamak scrape‐off layer simulations. This computational cost comes from the need to resolve individual collision events in high‐collisional regimes.
Oskar Lappi   +3 more
wiley   +1 more source

Improved Conservative Scheme for Lenard‐Bernstein Collisions in Gyrokinetic Turbulence Simulations

open access: yesContributions to Plasma Physics, EarlyView.
ABSTRACT Turbulence in the edge and scrape‐off layer regions plays a critical role for the performance of future magnetic confinement fusion power plants. Gyrokinetic simulations allow studying this regime with high fidelity. A key aspect in these regions is the high concentration of impurities, which can radiate energy, leading to significant losses ...
Andrew Ivan Sulimro   +3 more
wiley   +1 more source

Battery Pack for IoT Devices in a Harsh Outdoor Environment. [PDF]

open access: yesSensors (Basel)
Ševčík P   +3 more
europepmc   +1 more source

Monitoring Injected Drug Use in Greece Through Syringe Residue Analysis: A Multicity Study Within the ESCAPE Network

open access: yesDrug Testing and Analysis, EarlyView.
A total of 2121 used syringes were analyzed in Athens, Thessaloniki, and Patras between 2022 and 2024. Distinct drug‐use patterns were observed across the three cities. Benzodiazepines, pregabalin, methadone, and fentanyl were increasingly detected in 2024.
Christina Matiaki   +10 more
wiley   +1 more source

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