Results 71 to 80 of about 1,962,836 (339)

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source

A Review of Research on Urban Playability from a Social Justice Perspective

Land, 2023
Playability is an attribute that refers to the ability to stimulate individual responses or collective action in an immersive activity in an exploratory way. Playability is an important component of the enjoyment and well-being of urban dwellers, has the
Yang Ye, Yuhan Yang
doaj   +1 more source

Highly Secure In Vivo DNA Data Storage Driven by Genomic Dynamics

Advanced Science, EarlyView.
Integrated computational‐biological programming enables secure in vivo data storage by generating code tables from either genomes or gene regulatory networks, expanding the encryption key space by over 100 orders of magnitude. Storing code tables within synthetic genes, genomes, or gene regulatory networks adds an additional layer of security by ...
Jiaxin Xu, Yu Wang, Haibo Zhou, Mingen Li, Yang Wang, Lingwei Wang, Hui Mei, Junbiao Dai, Shanze Chen, Xiaoluo Huang   +9 more
wiley   +1 more source

The Continuing Advance and Retreat of Rural Settlement in the Northern Inland of Sweden

Journal of Northern Studies, 2020
In 1960, a range of leading rural geographers started a debate about population development and the “advance and retreat” of human settlement in sparsely populated rural areas, including in the inland north of Sweden.
D. Carson, Linda Lundmark, D. Carson
semanticscholar   +1 more source

A Novel Approach for Spatially Controllable High-Frequency Forecasts of Park Visitation Integrating Attention-Based Deep Learning Methods and Location-Based Services

ISPRS International Journal of Geo-Information, 2023
Forecasting tourism volume can provide helpful information support for decision-making in managing tourist attractions. However, existing studies have focused on the long-term and large-scale prediction and scarcely considered high-frequency and micro ...
Ming Lu, Qian Xie
doaj   +1 more source

“New” rural settlements – former urban-type settlements

Izvestiya Rossiiskoi akademii nauk. Seriya geograficheskaya, 2019
Since the 1920s, when the notion of urban-type settlement (UTS) was introduced in Russia, and until the 1980s the number of UTSs was constantly increasing. But since the 1990s, their rapid decline began, and by 2019 more than a third of them were transformed into rural settlements. In this article, the authors try to find out what the new villages the
A. S. Chuchkalov, A. I. Alekseev
openaire   +2 more sources

A synthetic measure of mortality using skeletal data from ancient cemeteries: the d index [PDF]

, 2018
Background: Due to the scarcity of written sources in ancient historical periods, and thanks to the development of increasingly sophisticated methods of excavation, recognition, publication, and interpretation, archaeology has played an important role in
Barbiera, Irene, Castiglioni, Maria, DALLA ZUANNA, GIANPIERO   +2 more
core   +2 more sources

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

Advanced Science, EarlyView.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo, Dongwon Park, Woosub Shin, Jongmin Kim   +3 more
wiley   +1 more source

The effects of indoor acoustic and visual environments on the mental health of older adults: a systematic review

Humanities & Social Sciences Communications
This systematic review aims to comprehensively assess the impact of indoor audiovisual environments on the mental health of older adults and provide recommendations for future research.
Jingyi Mu, Peiyu Li, Zhe Qin, Yimeng Feng, Cheng Zhang   +4 more
doaj   +1 more source

Winter Thermal Comfort and Perceived Air Quality: A Case Study of Primary Schools in Severe Cold Regions in China

Energies, 2020
In Northeast China, most classrooms in primary and secondary schools still use natural ventilation during cold days in winter. This study investigated the thermal comfort and the perceived air quality of children in primary schools in severe cold regions
Fusheng Ma, Changhong Zhan, Xiaoyang Xu, Guanghao Li   +3 more
doaj   +1 more source