Results 71 to 80 of about 53,637 (312)

Divergent Regulatory Effects of Jasmonic Acid on Tomato Lycopene Biosynthesis Under Light and Dark Conditions

Advanced Science, EarlyView.
This study reveals the mechanism by which jasmonic acid (JA) regulates lycopene synthesis under light and dark conditions. In light, JA activates SlMYC2, which suppresses SlPIF1a and promotes SlPSY1 expression. In darkness, JA induces the acetyltransferase SlNATA1, which acetylates the dark‐accumulated SlPIF1a, thereby repressing SlPSY1 expression ...
Jiayi Xu, Lingfeng He, Jialong Zhang, Hao Cui, Hongxin Li, Haijun Zhang, Jiaojiao Zhang, Lun Liu, Kunpeng Xu, Yang‐Dong Guo, Na Zhang   +10 more
wiley   +1 more source

Mapping hypertension control at the intersection of rurality and race and ethnicity, A study of US veterans

Journal of Maps
Disparities in hypertension control persist for rural-dwelling and for racial/ethnic minoritized Americans. However, the intersection of these characteristics, and their variation by geography, is not well known.
Michelle S. Wong, Kimberly E. Lind, Stephen Frochen, Anita H Yuan, Donna L. Washington   +4 more
doaj   +1 more source

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

Advanced Science, EarlyView.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li, Chen Zhang, Zhichao Zhang, Jiaheng Cheng, Qiuyan Gao, Long Gao, Xiaolin Zhao, Wei Yan, Yuanchao Wang, Wenwu Ye   +9 more
wiley   +1 more source

Chronic health conditions and health care affordability issues among U.S. rural and urban adults

Journal of Multimorbidity and Comorbidity
Purpose Chronic health conditions and rurality are associated with each other and with higher risks of medical debt. Less is known about the intersection of chronic conditions and health care affordability issues as they relate to rurality. The objective
Ingrid Jacobson, Alexis Swendener, Hannah MacDougall, Carrie Henning-Smith   +3 more
doaj   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Advanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo   +9 more
wiley   +1 more source

When Peace and Quiet Is Not Enough: Place-Shaping and the Role of Leaders in Sustainability and Quality of Life in Rural Estonia and Latvia

Land, 2020
Estonian and Latvian rural inhabitants enjoy many factors enhancing the quality of life, such as the peace and quiet of the countryside, fresh food and rural activities.
Joanna Storie, Edith Chenault, Mart Külvik, Simon Bell   +3 more
doaj   +1 more source

Is maternity care in Scotland equitable? Results of a national maternity care survey [PDF]

, 2019
Objective High-quality maternity care is key to long-term improvements in population health. However, even within developed welfare systems, some mothers and babies experience poorer care and outcomes.
Cheyne, Helen, Elders, Andrew, Hill, David, Milburn, Emma   +3 more
core   +2 more sources

An Increasing Misalignment Between Crop Distribution and Environmental Resources Under Climate Change in China

Advanced Science, EarlyView.
Climate change reshapes the spatial alignment between crop production and environmental resources. Using multi‐source data and a crop model, integrated climatic, water, and soil endowments for maize and wheat are quantified and compared with harvest distributions.
Zheng'e Su, Zhentao Zhang, Jin Zhao, Xia Liang, Chuang Zhao, Zhijuan Liu, Minghao Zhuang, Jing Sun, Bo Lu, Ke Liu, Johannes W. M. Pullens, Matthew T. Harrison, Deli Chen, Xiaoguang Yang   +13 more
wiley   +1 more source

Rurality and patients' hospital experience: A multisite analysis from a US healthcare system.

PLoS ONE
BackgroundThe association between rurality of patients' residence and hospital experience is incompletely described. The objective of the study was to compare hospital experience by rurality of patients' residence.MethodsFrom a US Midwest institution's ...
Iman Fawad, Karen M Fischer, Hanieh Sadat Tabatabaei Yeganeh, Kristine T Hanson, Laurie L Wilshusen, Yousif M Hydoub, Trevor J Coons, Tafi L Vista, Michael J Maniaci, Elizabeth B Habermann, Sagar B Dugani   +10 more
doaj   +1 more source

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source