Results 61 to 70 of about 1,020,400 (281)

Biallelic PIGB Variants Cause Motor Neuropathy with Conduction Blocks and Peripheral Nerve Hyperexcitability

open access: yesAnnals of Neurology, EarlyView.
Objective Glycosylphosphatidylinositol (GPI)‐anchored proteins play critical roles in nervous system function. Pathogenic variants in genes involved in GPI‐anchor biosynthesis cause early‐onset multisystem disorders known as inherited GPI deficiencies. We describe a novel neuromuscular phenotype associated with PIGB deficiency.
Gorka Fernández‐Eulate   +34 more
wiley   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Cooperation between Russia and Northeast Asian Countries in the development of the Russian Arctic Zone

open access: yesЭкономика и управление, 2019
In the 21st century, Russia plans its activities in the Arctic with the intention of developing its abundant resources and modernizing the Northern Sea Route (NSR).
Tat’yana V. Lezhenina
doaj  

Occupational accidents in Russia and the Russian Arctic

open access: yesInternational Journal of Circumpolar Health, 2013
According to official statistics, the rate of occupational accidents (OAs) and fatal injuries in Russia decreased about 5-fold and 2-fold, respectively, from 1975 to 2010, but working conditions during this period had the opposite trend; for example, the number of people who work in unfavourable and hazardous conditions (particularly since 1991) has ...
Dudarev, AA   +2 more
openaire   +4 more sources

Post With Care: How Language Use Influences the Effectiveness of CEOs' Climate‐Related Messages on Social Media

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Chief executive officers (CEOs) play a pivotal role in shaping public discourse on climate change through social media, yet how their language use affects the effectiveness of climate‐related posts remains unclear. Drawing on schema‐congruity theory and leader role expectations, we conceptualize certainty in language as congruent and anxiety ...
Ellen Weber   +4 more
wiley   +1 more source

Senior Arctic Official (SAO) Report to Ministers, Nuuk Greenland, 2011 [PDF]

open access: yes, 2011
Arctic Council Senior Arctic Officials' (SAO) Report to Ministers.
Arctic Council, -
core   +1 more source

Water Electrolysis Technologies for Extraterrestrial Water Resource Conversion

open access: yesEcoEnergy, EarlyView.
This paper reviews four water electrolysis technologies for extraterrestrial water conversion: alkaline water electrolysis, proton exchange membrane water electrolysis, solid oxide water electrolysis, and anion exchange membrane water electrolysis. It elaborates on their mechanisms, components, and integration, highlighting challenges such as water ...
Yawen Jiang   +6 more
wiley   +1 more source

Large Igneous Province Record Through Time and Implications for Secular Environmental Changes and Geological Time‐Scale Boundaries

open access: yesGeophysical Monograph Series, Page 1-26., 2021

Exploring the links between Large Igneous Provinces and dramatic environmental impact

An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Richard E. Ernst   +8 more
wiley  

+10 more sources

Revisiting Russian Presidency in the Arctic Council

open access: yesScientific and Analytical Herald of IE RAS, 2021
The article notes that in the period of preparation for the chairmanship of the Arctic Council (2021–2023), in order to further develop the Arctic zone of the Russian Federation, new strategic documents, a package of benefits and preferences for business development were prepared and approved, measures were taken for the sustainable development of ...
openaire   +2 more sources

Synergising Climate and Clean Air Governance in the EU: A Multilevel Analysis of Policy Integration

open access: yesEnvironmental Policy and Governance, EarlyView.
ABSTRACT Unlocking synergies while avoiding trade‐offs between climate and air pollution mitigation is key to policy effectiveness and cost‐efficiency. For maximum effect, these policies must be integrated not only horizontally within a governance level but also vertically across them.
Niklas Löther
wiley   +1 more source

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