Results 31 to 40 of about 64,613 (264)
Values and Experience of Neoliberal Reforms in Russian Regions: Dilemmas of Social Management
Мониторинг общественного мнения: экономические и социальные перемены, 2021 The article offers a critical look at the challenges emerging within the reforms of the social services sector in Russian regions carried out in line with the New Public Management (NPM) principles.
Никита Викторович Большаков +2 more
doaj +1 more source
Does the Shadow Sector Affect the Profitability of Organizations: A Regional Perspective [PDF]
Финансовый журналThe relevance of the study is due to the lack of works devoted to its topic and based on Russian data. The purpose is to estimate the impact of the shadow economy on the profitability of legally operating companies in Russia, taking into account regional
Liliya V. Barabanova +3 more
doaj +1 more source
Innovative Competitiveness Of Russian Regions
R-Economy, 2015 The article analyses the competitive challenges of Russian regional economies and proposes ways of selecting competitive priorities. The author assumes that selection of priorities for improving a region’s innovative competitiveness should involve not only its innovative RD potential but also the effects that innovative and socio-economic development ...
openaire +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Mapping young Russians’ perceptions of regional variation in Russian [PDF]
Journal of Linguistic Geography, 2021 AbstractThis paper studies the perception of regional variation in Russian among young Russian nonlinguists in Moscow, Perm, and Novosibirsk. I explore the labels used in 55 perceptual maps and categorize them in order to investigate the perceived character of regional variation among young Russians, including their explanations for regional variation.
openaire +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Annals of Clinical and Translational Neurology, EarlyView.Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Investment Priorities for Technological Breakthroughs Based on Scale Effect
Мир новой экономикиThe article presents an analytical approach to calculating the value of technological scale effect in regional industry clusters using econometric models.
E. V. Balatsky, N. A. Ekimova
doaj +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Advanced Science, EarlyView.. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li +15 more
wiley +1 more source