Results 61 to 70 of about 507,167 (231)

Five‐Grass‐Pollen Sublingual Immunotherapy Drops Are Efficacious and Well Tolerated in Adults: The RHAPSODY Phase III Trial

Allergy, EarlyView.
The RHAPSODY multinational study investigated 26 months of continuous treatment with 5‐grass‐pollen sublingual SLIT drops in adults with moderate‐to‐severe grass‐pollen‐induced allergic rhinoconjunctivitis. The primary efficacy endpoint (the average daily total combined score) showed statistically significant differences in favour of the active ...
Alain Didier, Ruta Gronskyte Juhl, Terrie Dalgaard, Antoine Chartier, Philippe Devillier   +4 more
wiley   +1 more source

Multidisciplinary Clinical Quality Indicators for Head and Neck Cancer: A Modified Delphi Study in Australia

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Monitoring delivery of cancer care is critical to improve outcomes in increasingly resource‐constrained settings. The aim of this study was to develop a priority set of multidisciplinary quality indicators (QIs) for benchmarking and monitoring the quality of care for head and neck cancer (HNC) in Australia.
Rebecca L. Venchiarutti, Ashleigh R. Sharman, Candice Donnelly, Nectarios Andrews, Martin Batstone, Sandeep Bhuta, Ruta Gupta, Claire Jeans, Jenny Lee, Eng H. Ooi, Mark Schifter, Puma Sundaresan, Swee T. Tan, Denyse Whelan, Takako (Eva) Yabe, Meiling Zhou, Carsten E. Palme, Jonathan R. Clark   +17 more
wiley   +1 more source

Estructura gráfica descriptiva de circuitos turísticos en Playa Gigante y Playa Amarillo en el municipio de Tola, Rivas, Nicaragua

La Calera
El aprovechamiento sostenible de los recursos naturales incluye diversas actividades que involucra tanto al turista como a la misma población de un determinado lugar.
Kimberly Joseth Martínez Guadamuz, Emelina Tapia Lorío, Rosa María Reyes Pérez   +2 more
doaj   +1 more source

New perspectives on head and neck allometry and ecomorphology in tetrapods

Biological Reviews, EarlyView.
ABSTRACT The skull and neck are vital parts of the body, influencing feeding ecology, habitat exploitation and locomotion. Numerous studies have therefore sought to understand how the size of these segments vary with ecology and scale with overall body size.
Alice E. Maher, Philip G. Cox, Thomas W. Maddox, James D. Gardiner, Karl T. Bates   +4 more
wiley   +1 more source

Long‐term neurological and psychiatric outcomes after paediatric arterial ischaemic stroke and cerebral sinovenous thrombosis

Developmental Medicine &Child Neurology, EarlyView.
Arterial ischemic stroke (AIS) or cerebral sinovenous thrombosis (CSVT) is a rare but serious event in children and adolescents. A descriptive long‐term (median 16 years) follow‐up study of patients revealed an increased risk of neurological and psychiatric diagnoses after AIS or CSVT, highlighting significant morbidity compared with the general ...
Jeanette Soenderlyng Springer, Søren Paaske Johnsen, Charlotte Olesen, Jan Brink Valentin, Ruta Tuckuviene   +4 more
wiley   +1 more source

Una propuesta para desarrollar turismo rural en los municipios de Zacatecas, México: las rutas agroculturales

PASOS Revista de Turismo y Patrimonio Cultural, 2011
El trabajo evaluó el potencial de los municipios de Zacatecas para desarrollar turismo de Rutas Agro-Culturales (RAC) en base a una serie de  recursos mediante el Índice del Evaluación de Rutas Agro-Culturales (IERAC); dando por resultado la Ruta del ...
María Eugenia González-Ávila
doaj   +3 more sources

Innovación en productos turísticos. Dark tourism: concepto, situación actual y casos de estudio [PDF]

, 2016
En este trabajo se conceptualiza la práctica del Dark Tourism (Turismo Oscuro), por el cual ha aumentado el interés en la literatura y por parte de los turistas en los últimos años.
Carrasco-Santos, Maria Jesus, Padilla-Melendez, Antonio   +1 more
core  

Psoriasis‐like inflammation induces structural and functional changes in mitochondria

The FEBS Journal, EarlyView.
Psoriasis‐like inflammation, induced by IL‐17, IL‐22, and TNF‐α in keratinocytes and fibroblasts, alters mitochondrial functions, suppressing respiration and increasing mitochondrial ROS production. It also triggers mitochondrial fragmentation, swelling, and cristae disassembly, alongside enhanced secretion of proinflammatory mediators driven by ...
Gabrielė Kulkovienė, Martyna Uldukytė, Sofiya Haluts, Milda Kairytė, Jonas Šoliūnas, Viktorija Šalčiūtė, Rūta Inčiūraitė, Jurgita Skiecevičienė, Monika Iešmantaitė, Ramunė Morkūnienė, Aistė Jekabsone   +10 more
wiley   +1 more source

Study of the effect of different diluent for Syringe Immersion Test on Rhipicephalus microplus larvae against macrocyclic lactones

Open Veterinary Journal
Background: Macrocyclic lactones (MLs) are pharmaceutical compounds extensively utilised in the management of Rhipicephalus microplus tick infestations in bovine populations.
Diego Robaina, Jessica Caballero, Gonzalo Suarez   +2 more
doaj   +1 more source

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

The FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova, Angelina Osipyan, Lili Zhang, Matthew R. Groves, Sandy Schmidt, Kristina Haslinger   +5 more
wiley   +1 more source