Results 91 to 100 of about 1,518 (207)

Psychometric Evaluation of the Facial and Total Vitiligo Area Scoring Index Instruments in the TRuE-V Phase 3 Studies

Dermatology and Therapy
Introduction This study reports psychometric testing of the facial and total Vitiligo Area Scoring Index quantitative clinical instruments (F-VASI [range: 0–3], T-VASI [range: 0–100], respectively) using data from two phase 3 randomized, vehicle ...
Kristen Bibeau, Kathleen Butler, Mingyue Wang, Konstantina Skaltsa, Iltefat H. Hamzavi   +4 more
doaj   +1 more source

Long-term safety and disease control with ruxolitinib cream among patients with atopic dermatitis based on previous medication history: Pooled results from two phase 3 studies [PDF]

, 2021
Andrew Blauvelt, Lawrence Eichenfeld, Michael E. Kuligowski, May E. Venturanza, Kang Sun, Jonathan I. Silverberg   +5 more
openalex   +1 more source

International survey of treatment practices for atopic dermatitis in pregnant and breastfeeding women: Physician perspectives

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 9, Page 1116-1124, September 2025.
Summary Background and Objectives Systemic treatment of pregnant/breastfeeding atopic dermatitis (AD) patients is challenging due to limited safety data. We explored treatment practices with systemic agents, including the guideline‐recommended cyclosporine as the first systemic choice as well as emerging therapies, in this vulnerable population ...
Manuel P. Pereira, Katarina Stevanovic, Emek Kocatürk, Cathrin Meesch, Ingrid van Hofman, Prema S. Vaswani, Jonathan A. Bernstein, Dayanne Bruscky, Herberto J. Chong‐Neto, Chia‐Yu Chu, Roberta Fachini Jardim Criado, Luis Felipe Ensina, Ana M. Giménez‐Arnau, Kiran Godse, Maia Gotua, Stamatios Gregoriou, Kanokvalai Kulthanan, Charlotte G. Mortz, Natasa Teovska Mitrevska, Esen Özkaya, Prajwal Pudasaini, Mara Morelo Rocha Felix, Catalina Rincón Pérez, Claudio Alberto Salvador Parisi, Gonzalo N. Ramón, Efstratios Vakirlis, Zuotao Zhao, Lisa A. Beck, Marjolein de Bruin‐Weller, Michael Cork, Norito Katoh, Thomas Werfel, Margitta Worm, Andreas Wollenberg, Torsten Zuberbier   +34 more
wiley   +1 more source

A randomized interventional study that compares treatments for vitiligo and anti-vitiligo cream

European Journal of Translational Myology
This study aimed to evaluate the efficacy of a novel combination therapy, AVC (Anti-Vitiligo Cream), compared to common treatments for vitiligo. A randomized interventional study was conducted on 1,000 patients with confirmed vitiligo, aged 7–70 years ...
Shahzad Shirzad, Mahdis Miladi
doaj   +1 more source

Adverse effects of Janus kinase inhibitors with relevance for daily practice in dermatology

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 9, Page 1127-1140, September 2025.
Summary Used since 2011 in the USA and 2012 in the EU, Janus kinase inhibitors (JAKi) are gaining increasing acceptance as a treatment for dermatological diseases such as atopic dermatitis, psoriasis, psoriatic arthritis, alopecia areata, chronic hand eczema and vitiligo.
Anika Rajput Khokhar, Kamran Ghoreschi, Julia Huynh   +2 more
wiley   +1 more source

Targeting the IL-15/CD122 signaling pathway: reversing TRM cell-mediated immune memory in vitiligo

Frontiers in Immunology
Vitiligo is a chronic autoimmune disorder in which melanocyte−specific CD8+ T cells destroy pigment−forming cells, producing persistent depigmented macules. Recurrence after treatment implicates tissue−resident memory T (TRM) cells that are maintained by
Xiangxi Su, Fang Liu
doaj   +1 more source

Systemic exposure and bioavailability of delgocitinib cream in adults with moderate to severe Chronic Hand Eczema

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 9, Page 1612-1621, September 2025.
Delgocitinib cream demonstrated minimal systemic exposure and no significant accumulation over time in patients with moderate to severe CHE. The systemic exposure was significantly lower versus oral administration (relative bioavailability: 0.6%). These findings suggest that no systemic pharmacological effect is expected with topical application of ...
Diamant Thaçi, Melinda Gooderham, Paola Lovato, Daniel Elenius Madsen, Anders Soehoel, Robert Bissonnette   +5 more
wiley   +1 more source

Long-Term Safety and Disease Control With Ruxolitinib Cream in Atopic Dermatitis: Results From Two Phase 3 Studies [PDF]

, 2021
Kim Papp, Jacek C. Szepietowski, Leon Kircik, Darryl Toth, Lawrence Eichenfeld, Seth Forman, Michael E. Kuligowski, May E. Venturanza, Kang Sun, Eric L. Simpson   +9 more
openalex   +1 more source

Chronic Hand Eczema (CHE): A Narrative Review [PDF]

Chronic hand eczema (CHE) is a common and challenging skin condition, characterized by persistent hand dermatitis which lasts over 3 months or recurs at least twice a year.
Costanzo A., Falcidia C., Ghezzi G., Mercuri S. R., Narcisi A., Paolino G., Valenti M.   +6 more
core   +1 more source

Ruxolitinib cream for the treatment of vitiligo – Authors' reply [PDF]

The Lancet, 2020
David, Rosmarin, Kathleen, Butler, Fiona, Kuo, John E, Harris   +3 more
openaire   +2 more sources