Results 31 to 40 of about 1,077,450 (288)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

The Impact of the Convective Blueshift Effect on Spectroscopic Planetary Transits

, 2011
We present here a small anomalous radial velocity (RV) signal expected to be present in RV curves measured during planetary transits. This signal is induced by the convective blueshift (CB) effect --- a net blueshift emanating from the stellar surface ...
Adam, Albrecht, Allende Prieto, Allende Prieto, Asplund, Avi Shporer, Cox, Dravins, Dravins, Dravins, Dravins, Dumusque, Evershed, Fabrycky, Forbes, Gaudi, Hirano, Holt, Howard, Queloz, Seager, Tim Brown, Winn, Winn, Winn   +24 more
core   +1 more source

The PTF Orion Project: a Possible Planet Transiting a T-Tauri Star [PDF]

, 2012
We report observations of a possible young transiting planet orbiting a previously known weak-lined T-Tauri star in the 7-10 Myr old Orion-OB1a/25-Ori region. The candidate was found as part of the Palomar Transient Factory (PTF) Orion project.
Agüeros, Andrew F. Boden, Andrew W. Howard, Avi Shporer, Baraffe, Baraffe, Bender, Benjamin J. Fulton, Boss, Branimir Sesar, Briceño, Briceño, Carl J. Grillmair, Carter, Chabrier, Chabrier, Chad F. Bender, Charles A. Beichman, Claret, Crockett, D. W. Hoard, David B. Levitan, David R. Ciardi, Dawn M. Gelino, Dawson, Dovi Poznanski, Eran O. Ofek, Esposito, Ford, Fortney, Gaudi, Geoffrey W. Marcy, Gray, Hernández, Hillenbrand, Howard, Huerta, Jason A. Surace, John R. Stauffer, Joshua S. Bloom, Julian C. van Eyken, Justin R. Crepp, Kaspar von Braun, Kraus, Kurucz, Levitan, Luisa M. Rebull, Mahmud, Mandel, Mansi M. Kasliwal, Marley, Marsh, Miralda-Escudé, Muirhead, Nguyen, Nicholas M. Law, Paula Szkody, Peter E. Nugent, Peter Plavchan, Plavchan, Prato, Rachel L. Akeson, Rappaport, Richard Walters, Robert M. Quimby, Russ Laher, S. Bradley Cenko, Setiawan, Shrinivas R. Kulkarni, Siess, Skrutskie, Solange V. Ramírez, Spiegel, Stephen R. Kane, Steve B. Howell, Suvrath Mahadevan, Timothy M. Brown, van Eyken, Wright   +78 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Modeling the RV and BVS of active stars [PDF]

, 2009
We present a method of modeling the radial velocity (RV) measurements which can be useful in searching for planets hosted by chromospherically active stars.
Bonfils, C. Migaszewski, Desidera, Desort, G. Nowak, Goździewski, Goździewski, Gray, Gray, Jenkins, Martínez Fiorenzano, Pepe, Queloz, Setiawan, Shkolnik   +14 more
core   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker, Abhijit Das, Andres Jimenez, Areeba Basit, Yike Jiang, Emily A. Smitherman, Heather Van Mater, Taylor Howard, Alexander J. Sandweiss, Kristen S. Fisher   +9 more
wiley   +1 more source

Improved Deep Multi-Patch Hierarchical Network For Handling Saturation In Image Deblurring

Array, 2022
The most active study topic in the field of computer vision is dealing with saturation in image deblurring. The Deep Multi Patch Framework (DMPHN) is primarily utilized in dynamic scene deblurring, and its fine-to-coarse hierarchical representation ...
Mahendra B.M., Savita Sonoli, Abhishek Ameta   +2 more
doaj   +1 more source

Measurement of the form-factor ratios for D+ --> K* l nu

, 1998
The form factor ratios rv=V(0)/A1(0), r2=A2(0)/A1(0) and r3=A3(0)/A1(0) in the decay D+ --> K* l nu, K* -->K-pi+ have been measured using data from charm hadroproduction experiment E791 at Fermilab.
A. Fernandez, A. Napier, A. Nguyen, A. Rafatian, A.B. d'Oliveira, A.C. dos Reis, A.F.S. Santoro, A.J. Schwartz, A.J. Slaughter, A.K. Tripathi, A.K.S. Santha, A.M. Halling, Altomari, B. Lundberg, B. Meadows, B. Quinn, Ball, Bhattacharya, C. Darling, C. Gobel, C. James, C. Zhang, D. Ashery, D. Mihalcea, D. Yi, D.A. Sanders, D.C. Langs, D.J. Summers, E. Wolin, E.M. Aitala, G. Blaylock, G. Herrera, G. Hurvits, G.F. Fox, Gilman, H.A. Rubin, H.S. Carvalho, I. Bediaga, Isgur, J. Leslie, J. Solano, J. Wiener, J.A. Appel, J.C. Anjos, J.J. Reidy, J.M. de Miranda, J.R.T. de Mello Neto, K. Denisenko, K. Gounder, K. O'Shaughnessy, K. Stenson, K. Thorne, K.C. Peng, Körner, L.M. Cremaldi, L.P. Perera, Ligeti, Lubicz, M. Sheaff, M.D. Sokoloff, M.V. Purohit, N. Witchey, N.K. Copty, N.R. Stanton, N.W. Reay, P. Gagnon, P.A. Kasper, P.R. Burchat, R. Weiss-Babai, R. Zaliznyak, R.A. Burnstein, R.A. Sidwell, R.H. Milburn, R.J. Stefanski, S. Amato, S. Banerjee, S. Kwan, S. MayTal-Beck, S. Radeztsky, S. Takach, S. Watanabe, S. Yoshida, S.B. Bracker, S.M. Yang, Schmidt, Stech, T. Carter, Wirbel   +87 more
core   +1 more source

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

Development of recycled masonry concrete blocks using crushed brick masonry debris: physical, mechanical, and sustainability characteristics

Journal of Asian Architecture and Building Engineering
The expansion of global infrastructure is contributing to the depletion of natural resources and other environmental concerns, primarily owing to the generation of construction and demolition waste.
Md Imran Ahmed, Namratha Bharadwaj, Ashwin M. Joshi, M. V. Renukadevi, S. M. Basutkar   +4 more
doaj   +1 more source