Results 11 to 20 of about 8,039 (70)

Support for a Connection Between Pediatric Bipolar Disorder and Tick-Borne Infections

Journal of Affective Disorders Reports, 2023
Aim: Infectious triggers and subsequent inflammatory responses may play important roles in psychiatric illness.1,2 Rates of both pediatric bipolar disorder (PBD) and tick-borne illnesses (TBIs) have concurrently significantly escalated in recent years.3 ...
Rosalie Greenberg, MD, FAPA, DFAACAP
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SARS-CoV-2, the blood-brain barrier, and neuroinflammation

Journal of Affective Disorders Reports, 2023
SARS-CoV-2 is the virus that produces COVID-19 and Long Covid. Whereas COVID-19 is primarily an acute respiratory disease, Long Covid is a chronic condition with many symptoms likely mediated through the CNS, including brain fog, fatigue, and cognitive ...
William A Banks, MD
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Inflammation hypothesis of depression by IL-17

Journal of Affective Disorders Reports, 2023
Despite high prevalence of depressive disorders, their etiopathogenesis has not been fully understood. Only around 2/3 of patients suffering from depression respond to the standard antidepressant treatment.
Katarzyna Bliźniewska-Kowalska
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Serum levels of neurofilament light-chain (NfL), a biomarker of axonal and synaptic damage, predict 5-year outcome in acutely ill schizophrenia patients

Journal of Affective Disorders Reports, 2023
Background: Disruptions of neuronal macro- and microcircuits in schizophrenia (SCZ) have been attributed to pathologies of neuronal connectivity. We hypothesized that during acute psychosis structural damage to axons and synapses occurs in a subset of ...
David Popovic, Kolja Schiltz, Henrik Dobrowolny, Gabriela Meyer-Lotz, Paul C. Guest, Wolfgang Jordan, Katrin Borucki, Nikolaos Koutsouleris, Bernhard Bogerts, Hans-Gert Bernstein, Alessandra Mandelli, Sabine Bahn, Roberto Furlan, Johann Steiner   +13 more
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Is a herpes viral protein responsible for foci of alarming presence of T cells in the brain of schizophrenia patients?

Journal of Affective Disorders Reports, 2023
Schizophrenia (SZ) is a devastating disease with a life time incidence of 1%. The distinguishing symptoms for diagnosis of the disorder are thought disorders like formal incoherence of thoughts, but also bizarre contents of thoughts, like thoughts been ...
Hans C. Klein
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A single-health system retrospective case series of electroconvulsive therapy for catatonic syndrome associated with anti-NMDAR encephalitis and new-onset psychosis of suspected immune origin

Journal of Affective Disorders Reports, 2023
Background: Anti-NMDA receptor encephalitis frequently presents with a wide range of psychiatric and behavioral symptoms such as catatonia and psychosis.
Sohag N Sanghani, Cristina Fernandez-Carbonell, Sanjeev V Kothare, Simona V Proteasa, Marc Gordon, Heela Azizi, Amy L Mastrangelo, Jason Andrus, Georgios Petrides, Souhel Najjar   +9 more
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PERSONALIZED IMMUNE DIAGNOSTICS: EPITOPE MAPPING OF THE IMMUNOME

Journal of Affective Disorders Reports, 2023
Statistical phage display is a highly complex, but rapid and efficient way to identify “binding peptides” from a unique and specially designed library. It avoids repeated selection rounds and can therefore provide much more complex data than just a few ...
M. Szardenings, N. Delaroque, M. Fischer, K. Kern, M. Puder, L. Ramirez Caballero, D. Wehrmann, E. Ehrentreich-Förster   +7 more
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Sexual Dimorphism of Microglia in High Trait Anxiety with a Particular Focus on Synaptic Pruning

Journal of Affective Disorders Reports, 2023
Microglia are the first responders to disruptions in homeostasis as well as crucial players contributing to synaptic refinement in the central nervous system (CNS).
Bilge Ugursu, Anupam Sah, Simone B. Sartori, Helmut Kettenmann, Nicholas Singewald, Susanne A. Wolf   +5 more
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Cerebrospinal fluid abnormalities in first- and multi-episode schizophrenia-spectrum disorders: impact of clinical and demographical variables

Journal of Affective Disorders Reports, 2023
Multiple lines of evidence indicate that immunological and inflammatory alterations contribute at least in a subgroup to the pathophysiology of schizophrenia.
Tatiana Oviedo-Salcedo, Elias Wagner
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Association between individuals’ locus of control and mental health during the COVID-19 pandemic

Journal of Affective Disorders Reports, 2023
Background: Locus of control (LOC), individuals’ perception that events occurring in life depend upon their own behavior and resources or not, has been shown to be associated with mental health disorders.
Filiz Eren, Isabelle Kousignian, Solène Wallez, Maria Melchior, Murielle Mary-Krause   +4 more
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