Results 51 to 60 of about 41,762 (99)

RTA-408 Protects Kidney from Ischemia-Reperfusion Injury in Mice via Activating Nrf2 and Downstream GSH Biosynthesis Gene

Oxidative Medicine and Cellular Longevity, 2017
Acute kidney injury (AKI) induced by ischemia-reperfusion is a critical conundrum in many clinical settings. Here, this study aimed to determine whether and how RTA-408, a novel oleanane triterpenoid, could confer protection against renal ischemia ...
P. Han, Zhiqiang Qin, Jingyuan Tang, Zhen Xu, Ran Li, Xuping Jiang, Chengdi Yang, Qian Xing, X. Qi, Min Tang, Jiexiu Zhang, B. Shen, Wei Wang, C. Qin, Wei Zhang   +14 more
semanticscholar   +1 more source

Youth mental health before and after the control of the coronavirus disease 2019: A nationally representative cohort study of Chinese college students

Journal of Affective Disorders Reports, 2021
Background: To investigate youth mental health changes over the course of coronavirus disease 2019 (COVID-19) using a national probability sample and longitudinal design.
Shun Gong, Lambert Zixin Li, Senhu Wang
doaj   +1 more source

Advanced adsorbents for ibuprofen removal from aquatic environments: a review

Environmental Chemistry Letters, 2023
The presence of pharmaceuticals in ecosystems is a major health issue, calling for advanced methods to clean wastewater before effluents reach rivers. Here, we review advanced adsorption methods to remove ibuprofen, with a focus on ibuprofen occurrence ...
A. Osman, A. Ayati, Mohamed Farghali, P. Krivoshapkin, Bahareh Tanhaei, H. Karimi-Maleh, Elena F. Krivoshapkina, Parsana Taheri, Chantal T. Tracey, A. Al-Fatesh, I. Ihara, David W. Rooney, Mika Sillanpaä   +12 more
semanticscholar   +1 more source

Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors

OncoTargets and Therapy, 2017
Background Omaveloxolone is a semisynthetic oleanane triterpenoid that potently activates Nrf2 with subsequent antioxidant function. We conducted a first-in-human Phase I clinical trial (NCT02029729) with the primary objectives to determine the ...
B. Creelan, D. Gabrilovich, J. Gray, Charles C. Williams, T. Tanvetyanon, E. Haura, J. Weber, G. Gibney, J. Markowitz, J. Proksch, S. Reisman, M. McKee, M. Chin, C. Meyer, S. Antonia   +14 more
semanticscholar   +1 more source

408 Cases of Genital Ambiguity Followed by Single Multidisciplinary Team during 23 Years: Etiologic Diagnosis and Sex of Rearing

International Journal of Endocrinology, 2016
Objective. To evaluate diagnosis, age of referral, karyotype, and sex of rearing of cases with disorders of sex development (DSD) with ambiguous genitalia. Methods. Retrospective study during 23 years at outpatient clinic of a referral center.
Georgette Beatriz De Paula, B. A. Barros, Stela Carpini, Bruna J Tincani, T. Mazzola, Mara Sanches Guaragna, C. S. C. Piveta, L. C. de Oliveira, J. Andrade, Guilherme Guaragna-Filho, Pedro Perez Barbieri, Nathalia Montibeler Ferreira, M. Miranda, E. Gonçalves, A. Morcillo, N. Viguetti-Campos, S. Lemos-Marini, R. B. D. P. Silva, A. P. Marques-de-Faria, M. de Mello, A. Maciel-Guerra, G. Guerra‐Júnior   +21 more
semanticscholar   +1 more source

MovieQA: Understanding Stories in Movies through Question-Answering [PDF]

Computer Vision and Pattern Recognition, 2015
We introduce the MovieQA dataset which aims to evaluate automatic story comprehension from both video and text. The dataset consists of 14,944 questions about 408 movies with high semantic diversity.
Makarand Tapaswi, Yukun Zhu, R. Stiefelhagen, A. Torralba, R. Urtasun, S. Fidler   +5 more
semanticscholar   +1 more source

Important factors in the observation dimensions of high school Yogo teachers to detect prodromal symptoms of mental health issues in adolescents

Journal of Affective Disorders Reports, 2021
Background: It is difficult to predict which type of student will subsequently develop psychosis. In Japan, the school nurse is called as a Yogo teacher and the role is similar to that of school nurses in Western countries. Our purpose was to investigate
Yukiko Masumoto, Shigeru Morinobu, Koichiro Fujimaki, Keiko Kasagi   +3 more
doaj   +1 more source

Resonant plasmonic micro-racetrack modulators with high bandwidth and high temperature tolerance

Nature Photonics, 2023
Resonant modulators encode electrical data onto wavelength-multiplexed optical carriers. Today, silicon microring modulators are perceived as promising to implement such links; however, they provide limited bandwidth and need thermal stabilization ...
M. Eppenberger, A. Messner, B. Bitachon, W. Heni, T. Blatter, P. Habegger, M. Destraz, Eva De Leo, Norbert Meier, Nino Del Medico, C. Hoessbacher, B. Baeuerle, J. Leuthold   +12 more
semanticscholar   +1 more source

The role of self-reported emotional regulation strategies in hoarding behaviours in a non-clinical adult sample

Journal of Affective Disorders Reports, 2023
Emotion regulation (ER) is implicated in various psychiatric conditions and individuals displaying hoarding behaviours report difficulties in their ER strategies.
Emily Bates, Alyson Dodd, Nick Neave
doaj   +1 more source

Virtual reality gaze exposure treatment reduces state anxiety during public speaking in individuals with public speaking anxiety: A randomized controlled trial

Journal of Affective Disorders Reports, 2023
Background: Public speaking anxiety (PSA) is a prevalent social anxiety affecting up to 30% of the population. Individuals with PSA often express fear of being evaluated by others and avoid eye contact.
Bernhard Fehlmann, Fabian D Mueller, Nan Wang, Merle K Ibach, Thomas Schlitt, Dorothée Bentz, Anja Zimmer, Andreas Papassotiropoulos, Dominique JF de Quervain   +8 more
doaj   +1 more source