Results 31 to 40 of about 2,408,727 (314)

Study of L-Arginine in Intestinal Lesions Caused by Ischemia-Reperfusion in Rats [PDF]

open access: yes, 2012
examine whether treatment with L-arginine (ARG), a substrate of nitric oxide biosynthesis, attenuated intestinal dysfunction caused by ischemia (I) and reperfusion (R), we treated rats with ARG (100 mg/kg intravenously) or saline solution (SS) before 60 ...
Bento, D. R. G. M.   +12 more
core   +1 more source

Caminhos e descaminhos da macrometrópole paulista: dinâmica econômica, condicionantes externos e perspectivas

open access: yesCadernos Metrópole, 2019
Resumo O presente artigo aborda aspectos econômicos relevantes do aglomerado urbano que constitui a Macrometrópole Paulista (MMP). Primeiramente, identificamos as principais dinâmicas associadas à globalização e as suas manifestações em São Paulo.
Alexandre Abdal   +3 more
doaj   +1 more source

Acute cocaine treatment increases thimet oligopeptidase in the striatum of rat brain [PDF]

open access: yes, 2012
Many studies indicate that thimet oligopeptidase (EC3.4.24.15; TOP) can be implicated in the metabolism of bioactive peptides, including dynorphin 1-8, alpha-neoendorphin, beta-neoendorphin and GnRH.
Andersen, Monica Levy   +13 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Comment on Neuromyelitis Optica: Potential Roles for Intravenous Immunoglobulin [PDF]

open access: yes, 2013
Universidade Federal de São Paulo, Neuroimmunol Clin, São Paulo, BrazilUniversidade Federal de São Paulo, Neuroimmunol Clin, São Paulo, BrazilWeb of ...
Bichuetti, Denis Bernardi   +1 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Exercise oxygen uptake efficiency slope independently predicts poor outcome in pulmonary arterial hypertension [PDF]

open access: yes, 2014
Universidade Federal de São Paulo UNIFESP, São Paulo Sch Med EPM, Dept Med, Pulm Vasc Grp, São Paulo, BrazilUniversidade Federal de São Paulo, EPM, Dept Med, Div Resp Dis,Pulm Funct & Clin Exercise Physiol U, São Paulo, BrazilQueens Univ, Dept Med, Div ...
Alencar, Maria Clara   +5 more
core   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick   +19 more
wiley   +1 more source

Trabalhadores das ferrovias: A Companhia Paulista de Estrada de Ferro, São Paulo, 1870-1920

open access: yesVaria História, 2016
Resumo Este artigo pretende compreender as relações entre ferrovia e transformações no mundo do trabalho, tomando por base empírica a Companhia Paulista de Estradas de Ferro. A pesquisa realizada organizou a documentação funcional (fés-de-ofício) de 1900
Ana Lucia Duarte Lanna
doaj   +1 more source

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