Results 71 to 80 of about 6,519 (158)
This EBMT Practice Harmonisation and Guidelines Committee consensus provides practical recommendations for the selection, timing and conduct of allogeneic transplantation in advanced‐stage mycosis fungoides and Sézary syndrome, aiming to optimize outcomes through early multidisciplinary collaboration and evidence‐based decision‐making.
Gandhi Damaj +26 more
wiley +1 more source
Abstract Adult T‐cell leukemia/lymphoma (ATLL) is a distinct type of peripheral T‐cell lymphoma (PTCL) driven by human T‐lymphotropic virus type I (HTLV‐1)–infected T cells, but diagnosis can be confounded by histological overlap with non‐ATLL PTCL. While molecular testing is the diagnostic gold standard in endemic areas, HTLV‐1/2 serology is often ...
Chang‐Tsu Yuan +10 more
wiley +1 more source
Single-cell heterogeneity in Sézary syndrome
: Sézary syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphoma (CTCL) with a median life expectancy of less than 4 years. Although initial treatment responses are often good, the vast majority of patients with SS fail to respond to
Terkild Brink Buus +19 more
doaj +1 more source
Evaluation of Sleep Disorders and Quality of Life in Patients With Mycosis Fungoides
ABSTRACT Background Mycosis fungoides (MF) is the most common cutaneous T‐cell lymphoma, presenting with variable clinical features that can be pruritic. Pruritus and the overall disease burden may disrupt sleep and diminish quality of life; yet, sleep disturbances in MF remain under‐investigated.
Seyed AmirReza Mohammadi +5 more
wiley +1 more source
Cutaneous T-cell lymphoma: Differential diagnostics of erythrodermic conditions
Erythroderma is a condition damaging at least 80–90 % of the skin surface, characterized by erythema and peeling. This condition may be a manifestation of various diseases of the skin and internal organs, including malignant lymphoproliferative disorders.
A. E. Karamova +3 more
doaj +1 more source
Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphoma [PDF]
BACKGROUND: Treatment for Cutaneous T Cell Lymphoma (CTCL) is generally not curative. Therefore, selecting therapy that is effective and tolerable is critical to clinical decision-making. Histone deacetylase inhibitors (HDACi), epigenetic modifier drugs,
Andrews, Jared M +5 more
core +2 more sources
ZEB proteins in leukemia : friends, foes, or friendly foes? [PDF]
. ZEB1 and ZEB2 play pivotal roles in solid cancer metastasis by allowing cancer cells to invade and disseminate through the transcriptional regulation of epithelial-to-mesenchymal transition.
Berx, Geert +5 more
core +1 more source
Folliculotropic Mycosis Fungoides: Update on Diagnosis, Clinicopathological Stage, and Management
Folliculotropic mycosis fungoides (FMF) is a rare subtype of MF, characterized by prominent folliculotropism in histopathology. Clinically, FMF exhibits polymorphic presentations, mainly including follicular papules, plaques, alopecia, and other nonspecific lesions, with a predilection for the head and neck region, leading to frequent misdiagnosis ...
Xingyu Li, Jie Liu, Nicola Pimpinelli
wiley +1 more source
Macrophage centripetal migration drives spontaneous healing process after spinal cord injury. [PDF]
Traumatic spinal cord injury (SCI) brings numerous inflammatory cells, including macrophages, from the circulating blood to lesions, but pathophysiological impact resulting from spatiotemporal dynamics of macrophages is unknown.
Edgerton, V Reggie +19 more
core +1 more source
STAT3 Activity and Function in Cancer: Modulation by STAT5 and miR-146b [PDF]
The transcription factor STAT3 regulates genes that control critical cellular processes such as proliferation, survival, pluripotency, and motility. Thus, under physiological conditions, the transcriptional function of STAT3 is tightly regulated as one ...
Frank, David A. +2 more
core +2 more sources

