Results 81 to 90 of about 6,519 (158)

An Itchy Problem: A Clinical Case of Crusted Scabies [PDF]

open access: yes
Scabies is an infestation of the skin by the mite Sarcoptes scabiei. A more severe form called crusted or Norwegian scabies may occur in immunosuppressed patients and the elderly.
Esteves, Alexandra   +4 more
core   +1 more source

Thymocyte selection-associated high mobility group box gene (TOX) is aberrantly over-expressed in mycosis fungoides and correlates with poor prognosis [PDF]

open access: yes, 2014
Mycosis fungoides (MF) often mimics the common chronic inflammatory skin diseases and is difficult to be diagnosed with certainty, partly because of the lack of well-characterized molecular markers.
Dutz, Jan P.   +9 more
core   +1 more source

Low-dose intermittent alemtuzumab in the treatment of Sézary syndrome: clinical and immunologic findings in 14 patients

open access: yesHaematologica, 2007
Background and Objectives Alemtuzumab may be effective in Sézary syndrome (SS), an aggressive cutaneous T-cell lymphoma, but is associated with severe hematologic toxicity and infections.
Maria Grazia Bernengo   +6 more
doaj   +1 more source

The Ectopic Expression of Meiosis Regulatory Genes in Cutaneous T-Cell Lymphomas (CTCL)

open access: yesFrontiers in Oncology, 2019
Cancer testis (CT) antigens, under normal circumstances are uniquely expressed in testicular germ cells. Recent research has shown that meiosis-specific CT (meiCT) antigens are ectopically expressed in cutaneous T-cell lymphoma (CTCL) and may contribute ...
Jennifer Gantchev   +7 more
doaj   +1 more source

Treatment patterns and clinical outcomes in patients with renal cell carcinoma in the UK: insights from the RECCORD registry [PDF]

open access: yes, 2015
Background The aim of the RECCORD registry was to gather real-world UK data on the use of targeted therapies in renal cell carcinoma (RCC) and assess clinical outcomes.
Abe   +29 more
core   +3 more sources

[18F]FDG PET/CT revealing extensive cutaneous involvement in Sézary syndrome

open access: yesNuclear Medicine Review
Sézary syndrome is a rare cutaneous T-cell lymphoma characterized by erythroderma and circulating malignant T cells. This study presents the case of a 31-year-old man with extensive skin involvement detected by 2-deoxy-2-[¹⁸F]fluoro-D-glucose positron ...
Yassir Benameur   +3 more
doaj   +1 more source

Staphylococcal alpha-toxin tilts the balance between malignant and non-malignant CD4+ T cells in cutaneous T-cell lymphoma

open access: yesOncoImmunology, 2019
Staphylococcus aureus is implicated in disease progression in cutaneous T-cell lymphoma (CTCL). Here, we demonstrate that malignant T cell lines derived from CTCL patients as well as primary malignant CD4+ T cells from Sézary syndrome patients are ...
Edda Blümel   +18 more
doaj   +1 more source

Romidepsin for the treatment of relapsed/refractory peripheral T cell lymphoma: prolonged stable disease provides clinical benefits for patients in the pivotal trial. [PDF]

open access: yes, 2016
BACKGROUND: Achievement of durable responses in patients with relapsed/refractory peripheral T cell lymphoma (PTCL) is challenging with current therapies, and there are few data regarding the potential benefits of continuing treatment in patients with ...
Balser, Barbara   +7 more
core   +5 more sources

Identification of a novel e8/a4 BCR/ABL fusion transcript in a case of a transformed Sézary syndrome

open access: yesHaematologica, 2007
This report deals with a case of Sézary syndrome, a rare peripheral T-cell lymphoproliferative disorder, in which cytogenetic analysis performed during the disease transformation revealed the presence of a t(9;22) (q34;q11.2) translocation.
Evelyne Callet-Bauchu   +5 more
doaj   +1 more source

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