Results 141 to 150 of about 1,568,099 (263)

Calcium Shock Enables Efficient and Programmable Particle Delivery for Genome Editing Applications

Advanced Science, EarlyView.
Classical transfection and transduction are inefficient, particularly with confluent cells and organoids, and lack cell type‐specific programmability. This study presents calcium shock (CaSh), a method that dramatically improves particle delivery into single cells, colonies, and organoids.
Nicole Vo, Lorena de Oñate, Maximillian Frank, Xian Hu, Sophie M. Blackburn, Dana V. Foss, Jasmine Villegas, Kunica Asija, Dirk Hockemeyer, Hongxia Fu, Raymond J. Monnat, Ross C. Wilson, Benjamin S. Freedman   +12 more
wiley   +1 more source

Monitoring Lead-Phosphorus Interactions Through ³¹P-NMR Used as a Sensor in Phosphine Functionalized Silica Gel Adsorbent. [PDF]

Gels
Badillo-Camacho J, Gutiérrez-Ortega JA, Shenderovich IG, Velázquez-Galván YG, Manríquez-González R.   +4 more
europepmc   +1 more source

Amorphization of Ethenzamide and Ethenzamide Cocrystals-A Case Study of Single and Binary Systems Forming Low-Melting Eutectic Phases Loaded on/in Silica Gel. [PDF]

Pharmaceutics, 2023
Trzeciak K, Wielgus E, Kaźmierski S, Pawlak T, Potrzebowski MJ.   +4 more
europepmc   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Calcium Impregnated Silica Gel in the Domino Reaction Involving Irreversible Aldol Addition, Dehydration, and Michael Addition. [PDF]

J Org Chem
Hwu JR, Bohara KP, Roy A, Huang WC, Hwang KC, Lin CC, Chuang KS, Lin SY, Tsay SC.   +8 more
europepmc   +1 more source

Experimental characterization of colloidal silica gel for water conformance control in oil reservoirs. [PDF]

Sci Rep, 2022
Ghaffari Z, Rezvani H, Khalilnezhad A, Cortes FB, Riazi M.   +4 more
europepmc   +1 more source

Super‐Enhancer‐Driven SOX4/SMAD3 Mediate Membrane Remodeling by Regulating Phospholipid Metabolism to Accelerate Leukemia Progression

Advanced Science, EarlyView.
Chronic myeloid leukemia blast phase (CML‐BP) poses a severe therapeutic challenge. This study reveals that the super‐enhancer‐driven transcription factors SOX4 and SMAD3 form a cooperative axis critical for disease progression. They co‐activate the oncogenic kinase AXL and promote phospholipid remodeling via LPCAT1 to facilitate its signaling ...
Enzhe Lou, Peilong Lai, Guanjie Peng, Bo Lu, Lizhen Jiang, Xinyue Li, Jinghong Chen, Ladi Mo, Qiong Mao, Haichuan Zhang, Jinxin Fang, Yi Meng, Aochu Liu, Yingyin Gao, Andong Huang, Wenhui Lin, Shiwen Hu, Zerong Guan, Xiaolan Ye, Zhenguo Liu, Liling Jiang, Yueyuan Zheng, Xianping Shi   +22 more
wiley   +1 more source

Long-Term Investigation of Nano-Silica Gel for Water Shut-Off in Fractured Reservoirs. [PDF]

Gels
Ali A, Al Ramadan M, Aljawad MS.
europepmc   +1 more source

Nanoporous silica gel can compete with the flower stigma in germinating and attracting pollen tubes. [PDF]

Front Plant Sci, 2022
Chichiriccò G, Poma A, Pace L.
europepmc   +1 more source

Investigation on a green olivine nano-silica source based activator in alkali activated slag-fly ash blends: Reaction kinetics, gel structure and carbon footprint

, 2017
X. Gao, Q. Yu, A. Lazaro, H. Brouwers
semanticscholar   +1 more source