Results 41 to 50 of about 11,381 (173)

Engineering Ultrasound Contrast Agents for Targeted Therapeutics: A Theranostic Approach to Drug Delivery, Gene Therapy, and Immunomodulation

Advanced NanoBiomed Research, EarlyView.
Ultrasound contrast agents, including microbubbles and nanobubbles, transform imaging and targeted therapy through precise engineering of size, shell composition, and surface properties. This review explores how these innovations enable tissue‐specific delivery, enhance therapeutic efficacy, and extend applications from vascular imaging to tumor ...
Ashkan Seza, Kimia Mozahheb Yousefi, Sara Minaeian   +2 more
wiley   +1 more source

AI‐Assisted Customizable SERS‐Based Aptasensor for Label‐Free, Rapid, and Sensitive Detection of Tau: Comparative Analysis Using Random Forest and Convolutional Neural Networks

Analysis &Sensing, EarlyView.
A customizable SERS‐based aptasensor platform integrates aptamer‐functionalized gold nanoparticles with machine learning models (RF and CNN) to detect tau protein, a key biomarker for Alzheimer's disease. This rapid, label‐free detection system achieves a detection limit of 100 pM, enabling early diagnosis and monitoring of disease progression.
Farbod Ebrahimi, Farshad Ebrahimi, Anjali Kumari, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Dissipative Heat Impact on the Non‐Newtonian Walter's B Nanoliquid Over an Elongating Surface Through a Permeable Medium

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The utilisation of viscoelastic Walter's B nanoliquid in engineering and biomedical applications gained substantial attention because of its ability to provide real‐time fluid behaviour, particularly in the heat flow mechanism. In particular, the flow of viscoelastic fluid over an elongating surface is useful in polymer processing and ...
Laxmipriya Swain, Subhajit Panda, S. R. Mishra, Rupa Baithalu   +3 more
wiley   +1 more source

Comparative Efficacy and Safety of Anakinra and Canakinumab in Patients With VEXAS Syndrome: An International Multicenter Study

Arthritis &Rheumatology, EarlyView.
Objective The aim of this study was to compare differences in clinical response, drug survival, and adverse event rates between anakinra and canakinumab in VEXAS (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) syndrome. Methods This multicenter international study includes patients with VEXAS from France, Israel, and Italy treated with ...
Tali Eviatar, Dafne Capelusnik, Corrado Campochiaro, Valentin Lacombe, Vincent Jachiet, Michael Zisapel, Iftach Sagy, Oshrat E. Tayer‐Shifman, David Ozeri, Shaye Kivity, Alessandro Tomelleri, Benjamin Terrier, Hagit Peleg, Thibault Comont, Karim Sacre, Pascal Woaye‐Hune, Laurent Arnaud, Estibaliz Lazaro, Vincent Grobost, Francois Lifermann, Maxime Samson, Samuel Ardois, Alice Garnier, Alexandre Maria, Alain Cantagrel, Aurore Meyer, Jean‐David Bouaziz, Mael Heiblig, Lorenzo Dagna, Elisa Diral, Olivier Kosmider, Ori Elkayam, Jérôme Hadjadj, Sophie Georgin‐Lavialle, Olivier Fain, Arsene Mekinian   +35 more
wiley   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists, Sodium‐Glucose Cotransporter‐2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases

Arthritis &Rheumatology, Accepted Article.
Objective GLP‐1 receptor agonists (GLP‐1RAs) and SGLT2 inhibitors (SGLT2is) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear. We compared ARD incidence following initiation of GLP‐1RAs, or SGLT2is, vs.
Derin Karacabeyli, Diane Lacaille, Na Lu, Hui Xie, J. Antonio Aviña‐Zubieta   +4 more
wiley   +1 more source

Supporting doctors' professional identity development through specialist training

Anatomical Sciences Education, EarlyView.
Abstract Anatomy‐centric specialties such as surgery, radiology, and anatomical pathology (AP) have workforce shortages, with attrition during the training phase proposed as a contributing factor. Current understanding of the reasons behind trainee attrition is limited, and there have been calls to increase the depth and richness of research in this ...
Shemona Y. Rozario, Melanie K. Farlie, Mahbub Sarkar, Michelle D. Lazarus   +3 more
wiley   +1 more source

Reduced Susceptibility to the Dunning–Kruger Effect in Autistic Employees

Autism Research, EarlyView.
ABSTRACT Evidence indicates that autistic individuals are less susceptible to social influence and cognitive biases than non‐autistic individuals. However, no studies have been conducted on the Dunning–Kruger effect (DKE) in autism. The DKE is a cognitive bias in which people with limited expertise in a specific domain overestimate their abilities. The
Lorne M. Hartman, Harley Glassman, Braxton L. Hartman   +2 more
wiley   +1 more source

Children With ASD Do Not Understand Hidden Emotions Before False Belief Attribution

Autism Research, EarlyView.
ABSTRACT Previous studies concluded that theory of mind (ToM) development is deviant in autism spectrum disorders (ASD). Typically developing children's ability to understand that one may hide their emotion would be acquired before false belief understanding in children with ASD (e.g., Peterson and Wellman 2019), but with contradictory results (e.g ...
Morgane Burnel, Stéphanie Durrleman, Anne Reboul, Jean Pylouster, Monica Baciu, Marcela Perrone‐Bertolotti   +5 more
wiley   +1 more source

Reduced Hand Specialization and Idiosyncratic Visuomotor Strategies in Autism During Naturalistic Object Manipulation

Autism Research, EarlyView.
ABSTRACT Autistic individuals exhibit altered perceptual and visuomotor behaviors, potentially due to reduced cortical specialization. The current study focuses on handedness, a robust marker of cerebral specialization, which is less right‐biased in autism.
Emily Fewster, Bat‐Sheva Hadad, Erez Freud   +2 more
wiley   +1 more source

System failure? Exploring the interplay of fear of failure, competition, cooperation and sense of belonging in education in England and Flanders

British Educational Research Journal, EarlyView.
Abstract Fear of failure is damaging in a host of ways yet is rife in many schools. Drawing on self‐worth theory, we explore whether fear of academic failure is higher in education systems with features that increase students' experiences of competition. To do this, we compare two very different education systems: England, where, for instance, national
Carolyn Jackson, Mieke Van Houtte
wiley   +1 more source