Results 161 to 170 of about 4,159,249 (256)

Parenteral artesunate compliance and hospital outcomes in children under five with suspected severe malaria in Sierra Leone. [PDF]

Public Health Action
Kamara ARY, Kamara IF, Thekkur P, Falama AM, Sillah-Kanu M, Lahai WK, Fiona OO, George A, Fofanah BD, Sesay N, Tengbe SM, Farma-Grant L, Bah A, Thomas F, Tejan YS, Kanu JS, Lakoh S, Mustapha M, Zachariah R, Chandrasekharan Prathija K, Kenneh SM.   +20 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Has Glioblastoma Five- and Ten-Year Survival Been Affected by New Treatment Algorithms in Population-Based Data? A Retrospective Swedish Survey Between 1958 and 2015. [PDF]

Cancers (Basel)
Milos P, Ehinger E, Visse E, Siesjö P.
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Latin American Group for Maturity (GDLAM) protocol: a reliable method to assess the functional autonomy of community-dwelling older men. [PDF]

PeerJ
Huerta Ojeda Á, Galdames Maliqueo S, Valderrama Muñoz M, Barahona-Fuentes G, de Villa Garduño R, Bravo Yapur M, Gacitúa Ruminot C, Navarro Vidal M, Salvo Román R, Pérez Corvalán T, Yeomans-Cabrera MM, Jorquera-Aguilera C, Jofré-Saldía E.   +12 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Did You Know: Erythropoiesis Is Regulated by Changes in Posture. [PDF]

Acta Physiol (Oxf)
Mazza OB, Gejl KD, Larsen S, Lundby C.
europepmc   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Elucidation of the key odorants contributing to the distinctive honey and sweet potato-like aroma in Wuyi black tea. [PDF]

Food Chem X
Lin Z, Xia M, Niu L, Chen G, Wang L, Huang J, Liu Z, Wang C.   +7 more
europepmc   +1 more source