Results 111 to 120 of about 612,422 (286)

S-genotype Assignments of Local Cultivars in Japanese Pear ‘Senryo’, ‘Kuroki’, and ‘Hogyoku’

Journal of the Japanese Society for Horticultural Science, 2009
Japanese pear exhibits gametophytic self-incompatibility controlled by a single S-locus with multiple alleles. The S-locus encodes an S-RNase as a stylar product, and 10 S-RNase alleles (S1 to S9, and Sk) have been cloned from major cultivars. To investigate the diversity of S-alleles in Japanese pear, we analyzed the S-genotypes of three local ...
Kazuma Okada, Carlos Castillo, Yutaka Sawamura, Tetsu Nakanishi, Takeshi Takasaki-Yasuda   +4 more
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Polymorphism of IL-1β rs16944(T/C) Associated with Serum Levels of IL-1β and Subsequent Stimulation of Extracellular Matrix Degradation Affects Intervertebral Disk Degeneration Susceptibility

Therapeutics and Clinical Risk Management, 2021
Zhao Wang,1 Xiaoxia Song,2 Qingbo Fang,3 Weige Xia,1 Aihua Luo2 1Department of Orthopedics, The Second Poverty Relief Hospital of Xinjiang Uygur Autonomous Region (The Fifth People′s Hospital of Xinjiang Uygur Autonomous Region), Urumqi, Xinjiang ...
Wang Z, Song X, Fang Q, Xia W, Luo A
doaj  

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Volume of Amygdala Subregions and Plasma Levels of Brain-Derived Neurotrophic Factor and Cortisol in Patients with s/s Genotype of Serotonin Transporter Gene Polymorphism of First-Episode and Drug-Naive Major Depressive Disorder: An Exploratory Study. [PDF]

Neurol Int, 2022
Okamoto N, Watanabe K, Tesen H, Ikenouchi A, Igata R, Konishi Y, Natsuyama T, Fujii R, Kakeda S, Kishi T, Iwata N, Yoshimura R.   +11 more
europepmc   +1 more source

S-genotype identification, genetic diversity and structure analysis of Italian sweet cherry germplasm

Tree Genetics & Genomes, 2017
In this study, 186 local sweet cherry accessions from 12 Italian regions, plus eight reference accessions, were analysed for the first time, using 13 microsatellite markers. Moreover, their S-incompatibility genotypes were identified with consensus primers for the S-RNase and SFB genes. A total of 161 unique genotypes were found; 18 groups of synonyms,
Marchese, A., Giovannini,, D., Leone,, A, ., Mafrica,, R, ., Palasciano,, M, ., Cantini,, C, ., DI VAIO, CLAUDIO, C, ., Salvador, De, F. R., Giacalone,, G, ., Caruso,, T, ., Marra, F. P.   +19 more
openaire   +5 more sources

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Hepatitis C infection: eligibility for antiviral therapies [PDF]

, 2005
Background Current treatments of chronic hepatitis C virus (HCV) are effective, but expensive and susceptible to induce significant side effects. Objectives To evaluate the proportion of HCV patients who are eligible for a treatment.
Belaiche, Jacques, Delwaide, Jean, El Saouda, R., Gerard, Christiane   +3 more
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Serotonin transporter genotype linked to adolescent substance use treatment outcome through externalizing behavior

Frontiers in Pediatrics, 2014
Meta-analyses suggest that the serotonin transporter linked polymorphic region (5-HTTLPR) short (S) allele, relative to the long (L) allele, is associated with risk for alcohol dependence, particularly among individuals with early onset antisocial ...
Tammy eChung, Jack eCornelius, Christopher Stephen Martin, Robert eFerrell, Stephen A. Maisto, Duncan B Clark   +5 more
doaj   +1 more source