Results 191 to 200 of about 612,422 (286)

Association of MMP9 and NOS3 Polymorphisms with Distinct Clinical Forms of Juvenile Scleroderma and Characteristics of Humoral Immunity. [PDF]

Int J Mol Sci
Osminina M, Podzolkova V, Litvinova M, Geppe N, Chebysheva S, Khachatryan L, Golovanova N, Kostina Y, Lazareva-Batyreva O, Polyanskaya A, Shpitonkova O, Subbotina T, Areian T, Podchernyaeva N.   +13 more
europepmc   +1 more source

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

Advanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li, Jing Yang, Weiran Wang, Chunyang Zuo, Liuling Pei, Yizan Ma, Rui Zhang, Yaru Fan, Huanhuan Ma, Yawei Li, Ruizhen Liu, Shuangxia Jin, Longfu Zhu, Jie Kong, Xianlong Zhang, Ling Min   +15 more
wiley   +1 more source

A Common Ancestry-Specific Sodium Channel Variant Increases Susceptibility to Drug-Induced QTc Prolongation: Evidence From a Large Biobank. [PDF]

Circulation
Stewart R, Lowery BD, Farber-Eger E, Wada Y, Roden DM, Wells QS, Davogustto G.   +6 more
europepmc   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Detection and Characterization of Sindbis Virus Genotype IV in Mosquitoes From Slovenia. [PDF]

Transbound Emerg Dis
Pozvek P, Korva M, Zakotnik S, Knapič T, Adam K, Resman Rus K, Grubelnik G, Trilar T, Ivović V, Avšič-Županc T, Knap N.   +10 more
europepmc   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source

BoGHV-4 Genotypic Diversity Shapes Inflammatory and Viral Gene Expression in Platelet-Rich Plasma-Supplemented Bovine Endometrial Cells. [PDF]

Viruses
López S, Álvarez I, Delgado S, Andreoli V, Urrutia Luna N, Yavorsky M, Pereyra S, Grolli S, González Altamiranda E, Pérez S, Verna A.   +10 more
europepmc   +1 more source

Cognitive and psychiatric aspects of mitochondrial encephalomyopathies [PDF]

, 2014
Inczédy-Farkas, Gabriella
core   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Photochemical Efficiency and Leaf Carbohydrates of Theobroma cacao L. Genotypes Under Different Light Regimes and Cultivation Systems. [PDF]

Plants (Basel)
da Vitória J, de Souza Oliveira V, Tercio Guasti A, Cezario Dias MA, da Silva Dias C, Nascimento de Santana E, Tesch Kuhlcamp K, de Oliveira Arantes L, Machado Filho JA, Batista Queiroz R, Spaggiari Souza CA, Romais Schmildt E, Dousseau-Arantes S.   +12 more
europepmc   +1 more source