Results 81 to 90 of about 612,422 (286)

The Investigation of HBV Pre-S/S Gene Mutations in Occult HBV Infected Blood Donors with anti-HBs Positive

Canadian Journal of Infectious Diseases and Medical Microbiology, 2022
Introduction. The coexistence of hepatitis B virus (HBV) and hepatitis B surface antibodies (anti-HBs) in occult hepatitis B virus infection (OBI) is a contradictory phenomenon, and the underlying mechanism is not fully understood. The characteristics of
Yan Guo, Yu Lan, Yuanyuan Jing, Bin Cai, Hanshi Gong, Yixin Zhang, Yong Duan   +6 more
doaj   +1 more source

S-genotype characterization of 13 North Western European pear (Pyrus communis) cultivars

Scientia Horticulturae, 2014
Due to the gametophytic self-incompatibility of European pear (Pyrus communis), S-compatible cultivars that flower synchronically are required in commercial pear orchards to ensure effective pollination and fruit production. The gametophytic self-incompatibility is controlled by a single locus (S-locus) encoding a polymorphic stylar ribonuclease (S ...
Muriel Quinet, Sophie Kelecom, Olivier Raspé, Anne-Laure Jacquemart   +3 more
openaire   +1 more source

Polymorphism of SFBB −γ and its use for S genotyping in Japanese pear (Pyrus pyrifolia) [PDF]

Plant Cell Reports, 2007
Japanese pear (Pyrus pyrifolia) exhibits the S-RNase-based gametophytic self-incompatibility where the pollen-part determinant, pollen S, had long remained elusive. Recent identification of S locus F-box brothers (SFBB) in Japanese pear and apple suggested that the multiple F-box genes are the pollen S candidates as they exhibited pollen specific ...
Hiroyuki, Kakui, Takeshi, Tsuzuki, Takato, Koba, Hidenori, Sassa   +3 more
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Shorter GT repeat polymorphism in the heme oxygenase-1 gene promoter has protective effect on ischemic stroke in dyslipidemia patients

Journal of Biomedical Science, 2010
Background The microsatellite polymorphism of heme oxygenase (HO)-1 gene promoter has been shown to be associated with the susceptibility to ischemic event, including coronary artery disease (CAD), myocardial infarction, and peripheral vascular disease ...
Chou Chia-Chi, Chiu Hou-Chang, Chen Jiunn-Rong, Bai Chyi-Huey, Chau Lee-Young, Pan Wen-Harn   +5 more
doaj   +1 more source

Accurate estimation of homologue-specific DNA concentration-ratios in cancer samples allows long-range haplotyping [PDF]

, 2011
Interpretation of allelic copy measurements at polymorphic markers in cancer samples presents distinctive challenges and opportunities. Due to frequent gross chromosomal alterations occurring in cancer (aneuploidy), many genomic regions are present at ...
Gad Getz, Matthew Meyerson, Scott L. Carter   +2 more
core   +1 more source

Effect of Serotonin Transporter 5HTTLPR Polymorphism on Gastrointestinal Intolerance to Metformin: A GoDARTS Study [PDF]

, 2016
OBJECTIVE: The mechanism causing gastrointestinal intolerance to metformin treatment is unknown. We have previously shown that reduced-function alleles of organic cation transporter 1 (OCT1) are associated with increased intolerance to metformin ...
Colin N.A. Palmer, Drago, Ewan R. Pearson, Kaixin Zhou, Roger Tavendale, Tanja Dujic, Wade   +6 more
core   +2 more sources

Determination of S-genotype in apple and sweet cherry cultivars released at Fruit Research Institute, Cacak [PDF]

Genetika, 2017
Apples and sweet cherries are generally characterized by self-incompatibility, which is controlled by the multiallelic locus S with gametophytic action. Thus the identification of S-genotype represents crucial information for fruit breeders and growers. The aim of this study was to identify the S-genotype of two apple (?Cacanska Pozna? and ?
Sladjana Maric, Sanja Radicevic, Milan Lukic, Radosav Cerovic, Svetlana Paunovic   +4 more
openaire   +3 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source