Results 81 to 90 of about 554,590 (276)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Evaluation of single and double-locus real-time PCR assays for methicillin-resistant Staphylococcus aureus (MRSA) surveillance

open access: yesBMC Research Notes, 2010
Background Methicillin-resistant Staphylococcus aureus (MRSA) is a human pathogen, representing an infection control challenge. Conventional MRSA screening takes up to three days, therefore development of rapid detection is essential.
Arielly Haya, Kolman Sara, Paitan Yossi
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The R3 Resistance to Phytophthora infestans in Potato is Conferred by Two Closely Linked R Genes with Distinct Specificities

open access: yesMolecular Plant-Microbe Interactions, 2004
The R3 locus of potato (Solanum tuberosum L.) confers full resistance to avirulent isolates of Phytophthora infestans, the causal agent of late blight.
Sanwen Huang   +6 more
doaj   +1 more source

D-mannose transport and metabolism in isolated enterocytes [PDF]

open access: yes, 2004
D-mannose transport and metabolism has been studied in enterocytes isolated from chicken small intestine. In the presence of Na+, the mannose taken up by the cells either remains free, is phosphorylated, is catabolized to H2O, or becomes part of membrane
Cano Rodríguez, María Mercedes   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Molecular S-genotyping of sweet cherry (Prunus avium L.) genetic resources

open access: yesHorticultural Science, 2019
Sweet cherries are self-incompatible, which is determined by a gametophytic self-incompatibility system (GSI). The self-incompatibility is controlled by a multi-allelic S-locus.
Josef Patzak   +3 more
doaj   +1 more source

C3H/HeNSlc mouse with low phospholipid transfer protein expression showed dyslipidemia

open access: yesScientific Reports, 2023
High serum levels of triglycerides (TG) and low levels of high-density lipoprotein cholesterol (HDL-C) increase the risk of coronary heart disease in humans.
Misato Kobayashi   +13 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Identification of S alleles associated with self-incompatibility in capuli (Prunus serótina subsp. capulí) samples by amplification of the Intron I of the S-RNasa gene

open access: yesACI Avances en Ciencias e Ingenierías, 2015
In plants, gametophytic self-incompatibility is a genetic mechanism regulated by the S locus, which has evolved to prevent self-fertilization. In fruit crops, information regarding the allelic composition of the S locus is essential for the establishment
Milton Gordillo   +3 more
doaj   +1 more source

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