Results 191 to 200 of about 73,130,393 (362)

Process Biochem.

open access: yes, 1999
Air pressure amplitude serves as a critical control parameter of periodic pressure solid state fermentation process. Effects of different air pressure amplitudes on cellulase production by Trichoderma viride-SL were investigated. Experiments were carried
Sun, T, Li, ZH, Liu, BH, Liu, DM
core  

Real-Time Temperature Measurement in a Vacuum Degasser Using Optical Pyrometry

open access: yes, 2007
The objective of the research was the development of a fiber-coupled, optical pyrometer for continuous temperature measurement in a vacuum degasser that reduces process time, enhances process control, and eliminates manual or robot-operated thermocouples.
Metrix, Peter Hues - Process   +3 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

An Automatic Method for Generation of CFD-Based 3D Compartment Models: Towards Real-Time Mixing Simulations

open access: yesBioengineering
This article aims to develop a method to automatically generate CFD-based compartment models. This effort to simplify mixing models aims at capturing the interactions between material transport and chemical/biochemical conversions in large-scale reactors.
Johan Le Nepvou De Carfort   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Fine Grained Process Modeling: an Experiment at British Airways

open access: yes, 1996
We report on the experimental application of process technology that we did at British Airways (BA) as part of the GOODSTEP project. The goal of GOODSTEP was to enhance and improve the functionality of an object database management ...
LAVAZZA, LUIGI ANTONIO   +6 more
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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