Results 291 to 300 of about 73,130,393 (362)

Cell-retention for lipid production in continuous Schizochytrium limacinum SR21 cultures fed with dark fermentation effluent. [PDF]

Bioresour Bioprocess
Täuber S, Ackermann L, Schittkowski H, Neubauer P, Junne S.   +4 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Nursing Process Data for Health Care Cost Prediction Using Machine Learning: Longitudinal Study. [PDF]

JMIR Nurs
Company-Sancho MC, González-Chordá VM, Orts-Cortés MI.   +2 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Numerical Simulation on Thermal Curing Behavior and Defect Formation Mechanism Analysis of Basalt Fiber-Reinforced Polymer Core Rods for Composite Cross-Arms. [PDF]

Polymers (Basel)
Zhang M, Duan Y, Zhang Z, Fu D.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Minimization of Welding Distortion in Large-Scale Welded Structures Using the MAG Method: Numerical and Physical Simulation of the Welding Process. [PDF]

Materials (Basel)
Mróz M, Czech R, Pikuła J, Spólnik M.
europepmc   +1 more source

Multi-scale fusion SDAM-net empowered by physics-informed conditional spectral augmentation enabling spectral feature assignment for the concurrent detection of nitrogen and sulfur in ship fuel oil. [PDF]

RSC Adv
Tian H, Zhang Y, Wu D, Hu C, Qiu P, Liu J, Fu C.   +6 more
europepmc   +1 more source

Further Evidences for the Sulfur Spillover on Carbon: Thermodynamic Aspects and Effects on Li-S Solid-State Batteries. [PDF]

Adv Sci (Weinh)
Piccolo F, Berger A, Risse S, Corominas RH, Erth W, Fuchs F, Andrade J, Schuster J, Armbrüster M, Adelhelm P.   +9 more
europepmc   +1 more source

Impact of smart and digital transformation on pharmacy intravenous admixture services in a tertiary-grade A hospital. [PDF]

Front Pharmacol
Xu CC, Zhang SY, Yuan RH, Li J.
europepmc   +1 more source