Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
In the mobile radio-frequency identification system, the accuracy and rapidity of tag recognition are undergoing great challenges. In this article, we proposed a novel tag anti-collision identification method based on tags’ priority called RPA in the ...
Liqian Zhang, Xueliang Fu, Honghui Li
doaj +1 more source
Surface penetrators for planetary exploration: Science rationale and development program [PDF]
Work on penetrators for planetary exploration is summarized. In particular, potential missions, including those to Mars, Mercury, the Galilean satellites, comets, and asteroids are described. A baseline penetrator design for the Mars mission is included,
Blanchard, M. B. +3 more
core +1 more source
Second unmanned gemini launch set for december 7 news release no. 64-296 [PDF]
Unmanned Gemini project - mission parameters, test objectives, and launch ...
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Discrepancy between subjective and objective assessments of wandering behaviours in dementia as measured by the
So Yayama +5 more
openalex +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Measurement of jet activity in top quark events using the eμ final state with two b-tagged jets in pp collisions at s = 8 $$ \sqrt{s}=8 $$ TeV with the ATLAS detector [PDF]
M. Aaboud +99 more
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source

