Results 281 to 290 of about 432,483 (291)

Maternal Inflammation During Pregnancy and Cord Blood Metabolomic Signatures in the Context of HIV Exposure. [PDF]

open access: yesMetabolites
Fu T   +7 more
europepmc   +1 more source

Calmodulin interaction with peptides from G-protein coupled receptors measured with S-Tag labeling

Biochemical and Biophysical Research Communications, 2005
We have developed a quantitative assay of calmodulin (CaM) binding to S-Tag labeled peptides derived from G-protein coupled receptor (GPCR) sequences. CaM binding of peptides derived from the third intracellular loop (i3) of mu opioid receptor (MOR) was confirmed and the CaM-binding motif refined. A MORi3 peptide with a Lys > Ala substitution--shown to
Ying, Zhang   +2 more
openaire   +2 more sources

Detection of pET-Vector Encoded, Recombinant S-Tagged Proteins Using the Monoclonal Antibody ATOM-2

Hybridoma, 2001
The 15-meric S-tag is a truncated form of the S-peptide, which builds together with the 103 amino acid large S-protein the whole ribonuclease S-protein. Its small size and excessive solubility have made the S-tag an excellent fusion partner in the production of recombinant proteins, and a large variety of applications have been reported using the S-tag
J H, Park   +4 more
openaire   +2 more sources

An interaction between S•tag and S•protein derived from human ribonuclease 1 allows site-specific conjugation of an enzyme to an antibody for targeted drug delivery

Journal of Immunological Methods, 2005
We have previously demonstrated that an antibody-avidin fusion protein could be used to deliver biotinylated enzymes to tumor cells for antibody-directed enzyme prodrug therapy. However, the presence of the chicken protein avidin suggests that immunogenicity may be a problem.
Tsuneaki, Asai   +2 more
openaire   +2 more sources

The Potential of Synthetic Tumor-Associated Glycoconjugates (S-TAGs) for Generating Monoclonal Antibodies for Breast Cancer Imaging and for Specific Immunotherapy

1989
The Thomsen Friedenreich (TF) antigen may be important for the detection and immunotherapy of a number of common cancers including breast cancer. Revealed on normal human erythrocytes by neuraminidase treatment, TF has been characterized as: β-D-Gal-(1–3)- α-GalNAc, attached to glycophorin or other glycoproteins through O-serine or O-threonine linkages
Grant MacLean   +9 more
openaire   +1 more source

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