Results 31 to 40 of about 8,620 (185)
The dual nature of TDC – bridging dendritic and T cells in immunity
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Multi-hop Backscatter Tag-to-Tag Networks [PDF]
We characterize the performance of a backscatter tag-to-tag (T2T) multi-hop network. For this, we developed a discrete component-based backscatter T2T transceiver and a communication protocol suite. The protocol composed of a novel (i) flooding-based link control tailored towards backscatter transmission, and (ii) low-power listening MAC.
Majid A. Y.+4 more
openaire +5 more sources
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
A eubacterial origin for the human tRNA nucleotidyltransferase? [PDF]
tRNA CCA-termini are generated and maintained by tRNA nucleotidyltransferases. Together with poly(A) polymerases and other enzymes they belong to the nucleotidyltransferase superfamily.
Aebi M.+12 more
core +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
B(Ds^+ -> l^+ nu) and the Decay Constant f_(D_s^+) [PDF]
I report final CLEO-c results on the purely leptonic decays of the D_s^+ -> l^+ nu, for the cases when l^+ is a mu^+ or tau^+, when it decays into pi^+ anti-nu, using 314/pb of data at 4.170 GeV.
Abulencia A+5 more
core +1 more source
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Production of Monoclonal and Polyclonal Antibodies Against PRRSV MLVD23-S tag Peptide Sequence [PDF]
Porcine reproductive and respiratory syndrome virus (PRRSV) is an RNA virus which belongs to the family Arteriviridae. Since its emergence in the late 1980’s and early 1990’s, PRRSV has had a major economic effect on the swine industry.
Bettin, Katelyn
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Tag Separation in Cardiac Tagged MRI [PDF]
In this paper we introduce a tag separation method for better cardiac boundary segmentation and tag tracking. Our approach is based on two observations in the cardiac tagged MR images: 1) the tag patterns have a regular texture; 2) the cardiac images without tag patterns are piecewise smooth with sparse gradients.
Junzhou Huang+4 more
openaire +3 more sources