Results 61 to 70 of about 432,483 (291)
ABSTRACT Children undergoing allogeneic stem cell transplantation often receive off‐label rituximab treatment for Epstein–Barr virus reactivation, using adult dosing without pediatric evidence. This project aims to develop a clinical decision support tool (CDSS) that provides evidence‐based dosing scenarios by analyzing real‐world patient data.
Birgit Burkhardt +2 more
wiley +1 more source
Metabolic engineering of Saccharomyces cerevisiae for overproduction of triacylglycerols
Triacylglycerols (TAGs) are valuable versatile compounds that can be used as metabolites for nutrition and health, as well as feedstocks for biofuel production.
Raphael Ferreira +5 more
doaj +1 more source
Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation. [PDF]
Nipah virus is an emergent paramyxovirus that causes deadly encephalitis and respiratory infections in humans. Two glycoproteins coordinate the infection of host cells, an attachment protein (G), which binds to cell surface receptors, and a fusion (F ...
Jardetzky, Theodore S +9 more
core +2 more sources
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed +5 more
wiley +1 more source
Functional Characterization of Soybean Diacylglycerol Acyltransferase 3 in Yeast and Soybean
Diacylglycerol acyltransferases (DGAT) function as the key rate-limiting enzymes in de novo biosynthesis of triacylglycerol (TAG) by transferring an acyl group from acyl-CoA to sn-3 of diacylglycerol (DAG) to form TAG.
Jinai Xue +11 more
doaj +1 more source
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura +5 more
wiley +1 more source
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser +6 more
wiley +1 more source
Tagging mortality experiments on Pacific mackerel, Pneumatophorus japonicus [PDF]
Two experiments were conducted to compare tagging mortality rates when Pacific mackerel are tagged using a traditional method and a modified method. Tagged and control fish in equal numbers were held in tanks on board the R/V ALASKA and observed for ...
Gregory, Paul A.
core
Global Analysis of Fragmentation Functions for Protons and Charged Hadrons
We present new sets of fragmentation functions for protons and inclusive charged hadrons obtained in combined NLO QCD analyses of single-inclusive hadron production in electron-positron annihilation, proton-proton collisions, and deep-inelastic lepton ...
de Florian, Daniel +2 more
core +1 more source
A Novel 3-Methyladenine DNA Glycosylase from Helicobacter pylori Defines a New Class within the Endonuclease III Family of Base Excision Repair Glycosylases [PDF]
The cloning, purification, and characterization of MagIII, a 3-methyladenine DNA glycosylase from Helicobacter pylori, is presented in this paper. Sequence analysis of the genome of this pathogen failed to identify open reading frames potentially coding ...
Boiteux, Serge +5 more
core +1 more source

