Results 161 to 170 of about 21,517,583 (302)

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

Advanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu, Kang Wang, Kwet Kyawl Yan, Zhikai Xu, Xuan Zhao, Xiangjun Bai, Zhanfei Li, Yuchang Wang   +7 more
wiley   +1 more source

Linezolid MIC creep among clinically significant <i>S. aureus</i>: a retrospective eight-year study. [PDF]

Front Antibiot
Eshwarappa CS, Gs VS, Shettar SR, Maheshwarappa YD, Sumana MN, A T, Mahale RP, Gs S, Rao MR, Shankaregowda R, Chitaragi VB, R D, Sr S, Murthy NS, Sai BS, Kumar VV.   +15 more
europepmc   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

Berberine Inhibits Eczematous Skin <i>S. aureus</i>-Induced Mast Cell/Basophil Activation and Modulates MAPK-Associated Gene Expression. [PDF]

Int J Mol Sci
Maskey AR, Kopulos D, Spears M, Wang ZZ, Mo X, Musa I, Yang N, Nowak-Wegrzyn A, Chung D, Maitland AL, Wang J, Tiwari RK, Sampson HA, Geliebter J, Li XM.   +14 more
europepmc   +1 more source

Dual‐Targeted Biomimetic MoSe2 Nanozymes for Enhancing Peri‐Implant Soft Tissue Integration

Advanced Science, EarlyView.
A dual‐targeting biomimetic nanozyme, MoSe2@SPMM, selectively targets Staphylococcus aureus and oxidatively stressed macrophages. Near‐infrared activation couples contact‐enhanced photothermal bacterial eradication with reactive oxygen species scavenging to disrupt the pathogenic–immunological amplification loop.
Minghao Zhou, Miaomiao Tian, Jingwei Yu, Jiaxin Kang, Miaomiao Chen, Yue Yuan, Lizhi Liu, Hongbo Wei   +7 more
wiley   +1 more source

Mechanical deformation inhibits growth and migration of <i>S. aureus</i> within submicrometer channels. [PDF]

mBio
DeFrates KG, Lee J, Jimenez G, Hwang JW, Pinho MG, Hernandez CJ.   +5 more
europepmc   +1 more source

Magneto‐Sono‐Enhanced Nanozyme Catalysis Drives ROS‐Mediated Pathogen Killing and Mitophagy‐Linked Inflammation Control in Bacterial Pneumonia

Advanced Science, EarlyView.
Nebulized BN@NF nanozymes integrate boron nanosheets with Nd‐doped iron phosphide to form a sono‐magneto‐responsive Z‐scheme heterostructure. Under ultrasound and magnetic activation, BN@NF amplifies ROS generation, eradicates bacteria, disrupts biofilms, and reshapes pulmonary inflammation through NF‐κB suppression, mitophagy promotion, and M1‐to‐M2 ...
Xiaofeng Luo, Yundi Wu, Shuai Zhang, Huanran Qu, Shiyang Shao, Jianqiang Chen, Xilong Wu   +6 more
wiley   +1 more source

Discovery of a Thermostable Nigerose Phosphorylase for the Efficient Chemoenzymatic Radiosynthesis of a <i>S. aureus</i>-Targeted ¹⁸F-Disaccharide. [PDF]

J Nucl Med
Kim JM, Lee SH, Dhaene S, Ancona A, Kim J, López-Álvarez M, Sorlin AM, Blecha J, Zou W, Neumann KD, Mangiatordi GF, Lee E, Nidetky B, Flavell RR, Seo Y, Engel J, Ohliger MA, Desmet T, Wilson DM.   +18 more
europepmc   +1 more source

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

Advanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann, Adam Brooks Goodman, Myddelton C. Parker, Mark Garren, Ji Eun Park, Chad Schmiedt, Hitesh Handa, Elizabeth J. Brisbois   +7 more
wiley   +1 more source

Comparative study of recurrent mastitis caused by methicillin-resistant Staphylococcus aureus and non-MRSA S. aureus in Holstein-Fresian cows. [PDF]

J Vet Med Sci
Janevski D.
europepmc   +1 more source