Clinicians often concurrently tackle critical challenges including emergency hemorrhage, secondary infection, and the elusive tracking of biodegradation of conventional hemostatic agents for complex wounds. Here, we report an intelligent hemostatic sponge (spCS@AIE) by incorporating aggregation‐induced emission (AIE) nanoparticles with short‐wave ...
Zhicheng Liu +12 more
wiley +1 more source
The Difluoroboranyl-Fluoroquinolone Derivative "7a" Inhibits Bacterial DNA Gyrase and Exhibits Potent Activity Against Ciprofloxacin-Resistant <i>S. aureus</i> In Vitro and In Vivo Using an Acute Pneumonia Model. [PDF]
Veyna-Hurtado LA +7 more
europepmc +1 more source
A super‐slippery liquid‐infused composite organogel is engineered by localized interfacial grafting between hydrogel and oleogel networks, endowing the coating with a durable, multifunctional marine‐protective interface. Dynamic antifouling surfaces have emerged as a promising alternative, offering the potential for eco‐friendly and high‐performance ...
Mengsheng Xia +6 more
wiley +1 more source
Immune dysfunction during S. aureus biofilm-associated implant infections: opportunities for novel therapeutic strategies. [PDF]
Brandquist ND, Kielian T.
europepmc +1 more source
Total Synthesis of Sacrolide A and Cytotoxic Evaluation
Isolated from the edible cyanobacterium Aphanothece sacrum, sacrolide A is a highly potent antimicrobial and cytotoxic metabolite. Its total synthesis via a convergent strategy enabled accurate assessment of its effects on liver and colon cells, offering new insights into its bioactivity and potential health risks.
Priyanka Kataria +7 more
wiley +1 more source
Vagus nerve stimulation alleviates S. aureus-induced mastitis by regulating gut microbiota S24-7-PPARγ and NF-ΚB/NLRP3 signaling in mice. [PDF]
He Y +10 more
europepmc +1 more source
The conversion of 1‐halogenothioxanthones into 1‐(acetylamino) derivatives and their NaH‐mediated cyclization have been optimized. This rapid method yields thiochromeno[4,3,2‐de]quinol‐2‐ones that exhibit promising in vitro anticancer activity. Institute and/or researcher Bluesky usernames: https://bsky.app/profile/iscr‐rennes.bsky.social.
Najet Ballagha +12 more
wiley +1 more source
S. aureus exposure during cutaneous antigen sensitization causes basophil- and interleukin-4-dependent exaggerated food anaphylaxis. [PDF]
Das M +27 more
europepmc +1 more source
Improved Incorporation of Arylglycines Into Ramoplanin Sequences via Solid‐Phase Peptide Synthesis
The incorporation of arylglycines using solid‐phase peptide synthesis remains challenging due to the sensitivity of these residues for epimerization. Here, exploring multiple conditions for the incorporation of arylglycine residues into peptides using SPPS demonstrates how small changes to current synthesis protocols can lead to significant ...
Edward Marschall +3 more
wiley +1 more source
Antibacterial Evaluation of Tricyclic Antidepressants Against <i>S. aureus</i> and the Possible Pathways of the Mechanism of Action. [PDF]
de Farias Cabral VP +14 more
europepmc +1 more source

