Results 1 to 10 of about 70,048 (237)

Isolation of Streptococcus mutans temperate bacteriophage with broad killing activity to S. mutans clinical isolates [PDF]

iScience, 2023
Summary: Bacteriophages are expected to be therapeutic agents against infectious diseases. Streptococcus mutans are involved in dental plaque formation related to dental caries and periodontitis. In S.
Katsuhito Sugai, Miki Kawada-Matsuo, Mi Nguyen-Tra Le, Yo Sugawara, Junzo Hisatsune, Jumpei Fujiki, Hidetomo Iwano, Kotaro Tanimoto, Motoyuki Sugai, Hitoshi Komatsuzawa   +9 more
doaj   +4 more sources

Lactobacillus plantarum Disrupts S. mutans-C. albicans Cross-Kingdom Biofilms. [PDF]

Front Cell Infect Microbiol, 2022
Dental caries, an ecological dysbiosis of oral microflora, initiates from the virulent biofilms formed on tooth surfaces where cariogenic microorganisms metabolize dietary carbohydrates, producing acid that demineralizes tooth enamel. Forming cariogenic biofilms, Streptococcus mutans and Candida albicans are well-recognized and emerging pathogens for ...
Zeng Y, Fadaak A, Alomeir N, Wu TT, Rustchenko E, Qing S, Bao J, Gilbert C, Xiao J.   +8 more
europepmc   +4 more sources

Dextranase enhances nanoparticle penetration of <i>S. mutans</i> biofilms. [PDF]

J Oral Microbiol
BACKGROUND/OBJECTIVE: Cariogenic biofilms possess a rich extracellular polysaccharide (EPS) matrix, which can reduce the penetration of anticaries agents such as nanoparticle-based technologies. The aim of this study was to assess the potential of dextranase, an EPS-degrading enzyme, to enhance nanoparticle penetration into Streptococcus mutans in ...
DeCesaris DS, Hayashi MAL, Vickerman MM, Rickard AH, Tenuta LMA.   +4 more
europepmc   +3 more sources

Proline-rich protein from S. mutans can perform a competitive mineralization function to enhance bacterial adhesion to teeth [PDF]

Scientific Reports, 2022
A proline-rich region was found in Streptococcus mutans (S. mutans) surface antigen I/II (Ag I/II). The functions of this region were explored to determine its role in the cariogenic abilities of S.
Kun Tian, Chengwei Xiao, Yue Chen, Min Zhou, Jun Guo, Xiaohua Ren, Qin Du   +6 more
doaj   +2 more sources

Norspermidine changes the basic structure of S. mutans biofilm. [PDF]

Mol Med Rep, 2017
The factors regulating the assembly of the three-dimensional structure of Streptococcus mutans biofilms remain obscure. Polyamines are essential in biofilm formation of certain bacteria. Norspermidine, an unusual polyamine, has been a controversial polyamine that can lead to biofilm disassembly. However, the role of norspermidine in S.
Ou M, Ling J.
europepmc   +4 more sources

The S. mutans mntE gene encodes a manganese efflux transporter. [PDF]

Mol Oral Microbiol, 2020
Abstract Streptococcus mutans is a colonizer of the human dentition, and under conditions of dysbiosis is the primary causative agent of dental caries. The pathogenic potential of S.
O'Brien J, Pastora A, Stoner A, Spatafora G.   +3 more
europepmc   +4 more sources

S. Mutans Effects On Gut Microbiota Of Mice

International Dental Journal
Aim or purpose: To investigate the effects of Streptococcus mutans on intestinal tissues and intestinal flora in healthy mice and mice with ulcerative colitis (UC), elucidating the potential correlation between cariogenic microorganisms and intestinal ...
Si Yu, Yao Liu
doaj   +2 more sources

SloR-SRE binding to the <i>S. mutans mntH</i> promoter is cooperative. [PDF]

J Bacteriol
ABSTRACT Streptococcus mutans is a commensal member of the plaque microbiome. It is especially prevalent when dietary sugars are available for S. mutans fermentation, generating acid byproducts that lower plaque pH and foster tooth decay.
Ziogas M, Drummond I, Todorovic I, Kraczkowsky K, Han Y, Zhang H, Wu H, Spatafora G.   +7 more
europepmc   +3 more sources

Targeting S. mutans biofilms: a perspective on preventing dental caries. [PDF]

Medchemcomm, 2019
This review aims to provide an overview of the current small molecule strategies used for targeting S. mutans biofilms, and a perspective of the future for the field.
Scharnow AM, Solinski AE, Wuest WM.
europepmc   +4 more sources

Synthetic antigen-binding fragments (Fabs) against S. mutans and S. sobrinus inhibit caries formation. [PDF]

Sci Rep, 2018
AbstractStreptococcus mutansandStreptococcus sobrinusare the main causative agents of human dental caries. Current strategies for treating caries are costly and do not completely eradicate them completely. Passive immunization using nonhuman antibodies against Streptococcal surface antigens has shown success in human trials, however they often invoke ...
Alam MK, Zheng L, Liu R, Papagerakis S, Papagerakis P, Geyer CR.   +5 more
europepmc   +4 more sources