Results 1 to 10 of about 20,287,569 (319)

Automated glycan assembly of a S. pneumoniae serotype 3 CPS antigen. [PDF]

Beilstein J Org Chem, 2016
Vaccines against S. pneumoniae, one of the most prevalent bacterial infections causing severe disease, rely on isolated capsular polysaccharide (CPS) that are conjugated to proteins.
Weishaupt MW, Matthies S, Hurevich M, Pereira CL, Hahm HS, Seeberger PH.   +5 more
europepmc   +6 more sources

Streptococcus pneumoniae interactions with the complement system

Frontiers in Cellular and Infection Microbiology, 2022
Host innate and adaptive immunity to infection with Streptococcus pneumoniae is critically dependent on the complement system, demonstrated by the high incidence of invasive S.
Eliza Gil, Mahdad Noursadeghi, Jeremy S. Brown   +2 more
doaj   +2 more sources

Splenic Ly6G^high mature and Ly6G^int immature neutrophils contribute to eradication of S. pneumoniae. [PDF]

J Exp Med, 2017
The spleen plays an integral protective role against encapsulated bacterial infections. Our understanding of the associated mechanisms is limited to thymus-independent (TI) antibody production by the marginal zone (MZ) B cells, leaving the contribution ...
Deniset JF, Surewaard BG, Lee WY, Kubes P.   +3 more
europepmc   +2 more sources

A Multicenter Evaluation of the US Prevalence and Regional Variation in Macrolide-Resistant S. pneumoniae in Ambulatory and Hospitalized Adult Patients in the United States. [PDF]

Open Forum Infect Dis, 2021
Gupta V, Yu KC, Schranz J, Gelone SP.
europepmc   +3 more sources

StkP- and PhpP-Mediated Posttranslational Modifications Modulate the S. pneumoniae Metabolism, Polysaccharide Capsule, and Virulence. [PDF]

Infect Immun, 2023
Kant S, Sun Y, Pancholi V.
europepmc   +2 more sources

Establishment of an ELISpot Assay to Detect Cellular Immunity against S. pneumoniae in Vaccinated Kidney Transplant Recipients. [PDF]

Vaccines (Basel), 2021
Gäckler A, Mülling N, Völk K, Wilde B, Eisenberger U, Rohn H, Horn PA, Witzke O, Lindemann M.   +8 more
europepmc   +3 more sources

Integrated immunoinformatics and subtractive proteomics approach for multi-epitope vaccine designing to combat S. pneumoniae TIGR4. [PDF]

Front Mol Biosci, 2023
Ashgar SS, Faidah H, Bantun F, Jalal NA, Qusty NF, Darwish A, Haque S, Janahi EM.   +7 more
europepmc   +3 more sources

CRH promotes S. pneumoniae growth in vitro and increases lung carriage in mice [PDF]

Frontiers in Microbiology, 2015
Streptococcus pneumoniae (S. pneumoniae), a commensal across the nasal passages, is responsible for the majority of infectious pneumonia cases worldwide. Previous studies have shown that hormonal factors may be influential in regulating S.
Colette Georgette Ngo Ndjom, Colette Georgette Ngo Ndjom, Harlan Pierre Jones   +2 more
doaj   +2 more sources

The diagnostic value of metagenomic next-generation sequencing for identifying Streptococcus pneumoniae in paediatric bacterial meningitis

BMC Infectious Diseases, 2019
Background There is currently no research on the diagnostic value of metagenomic next-generation sequencing (mNGS) for a single pathogens in CSF.
Xi-xi Zhang, Ling-yun Guo, Lin-lin Liu, Ao Shen, Wen-ya Feng, Wen-hua Huang, Hui-li Hu, Bing Hu, Xin Guo, Tian-ming Chen, He-ying Chen, Yong-qiang Jiang, Gang Liu   +12 more
doaj   +2 more sources

Blocking HXA₃-mediated neutrophil elastase release during S. pneumoniae lung infection limits pulmonary epithelial barrier disruption and bacteremia. [PDF]

mBio
Xu S, Tan S, Romanos P, Reedy JL, Zhang Y, Mansour MK, Vyas JM, Mecsas J, Mou H, Leong JM.   +9 more
europepmc   +2 more sources