Results 221 to 230 of about 22,716,326 (258)
Acta Paediatrica, EarlyView.ABSTRACT Aim To assess the incidence of culture‐proven sepsis and examine the correlation between positive blood cultures and nurse staffing in a Level IV neonatal intensive care unit (NICU). Methods This retrospective cohort study included neonates with ≥ 1 positive blood culture and signs of infection between 2018 and 2023.
A. Gudiksen +7 more
wiley +1 more source
Identifying genes associated with invasive disease in S. pneumoniae by applying a machine learning approach to whole genome sequence typing data. [PDF]
Sci Rep, 2019 Obolski U +7 more
europepmc +1 more source
Acta Paediatrica, EarlyView.ABSTRACT Aim We characterized infections after international travel and identified predictors of severe infection to refine management. Methods We conducted a retrospective cross‐sectional analysis of children aged 0–18 years presenting to Helsinki University Hospital Emergency Department within 90 days of international travel between January 1, 2015 ...
Tuula Pelkonen, Svetlana Vakkilainen
wiley +1 more source
Increased susceptibility of airway epithelial cells from ataxia-telangiectasia to S. pneumoniae infection due to oxidative damage and impaired innate immunity. [PDF]
Sci Rep, 2019 Yeo AJ +7 more
europepmc +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.In this nationwide study of patients with inflammatory bowel disease, TNF inhibitor use was associated with higher bloodstream infection rates, whereas vedolizumab and ustekinumab was not. Associations differed by pathogen species, and concomitant glucocorticoid use was associated with higher infection rates.
Cæcilie Leding +4 more
wiley +1 more source
Proteomic and bioinformatic pipeline to screen the ligands of S. pneumoniae interacting with human brain microvascular endothelial cells. [PDF]
Sci Rep, 2018 Jiménez-Munguía I +9 more
europepmc +1 more source
Cancer Science, EarlyView.tRNA‐derived small RNAs (tsRNAs) function in digestive cancers across three scales: intracellular translational and metabolic control, extracellular vesicle–mediated immune remodeling, and systemic and host–microbe communication. This review organizes these mechanisms by evidence strength, from well‐established intracellular roles to emerging ...
Wang Xitan, Li Han
wiley +1 more source
Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria
Cancer Science, EarlyView.Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren +11 more
wiley +1 more source
Clinical Otolaryngology, EarlyView.ABSTRACT Background Antibiotics are frequently prescribed for acute exacerbations of chronic rhinosinusitis (CRS). However, antimicrobial resistance presents a challenge for the ongoing and future management of CRS patients. Objective This study aims to examine the current and past microbiological yield and antimicrobial resistance profile in a ...
Timoleon Siempis +3 more
wiley +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematologic disorder caused by a defect of glycosylphosphatidyl‐anchored proteins, leading to an uncontrolled complement‐mediated hemolysis. The advent of complement inhibitors in clinical practice radically changed patients' outcomes and survival.
Bruno Fattizzo +8 more
wiley +1 more source