Results 81 to 90 of about 13,207 (147)

Mitigating off‐target effects of small RNAs: conventional approaches, network theory and artificial intelligence

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 2, Page 340-379, January 2025.
Abstract Three types of highly promising small RNA therapeutics, namely, small interfering RNAs (siRNAs), microRNAs (miRNAs) and the RNA subtype of antisense oligonucleotides (ASOs), offer advantages over small‐molecule drugs. These small RNAs can target any gene product, opening up new avenues of effective and safe therapeutic approaches for a wide ...
Zoltán Bereczki   +14 more
wiley   +1 more source

An application of the Maslov complex germ method to the 1D nonlocal Fisher-KPP equation

open access: yes, 2018
A semiclassical approximation approach based on the Maslov complex germ method is considered in detail for the 1D nonlocal Fisher-Kolmogorov-Petrovskii-Piskunov equation under the supposition of weak diffusion.
Shapovalov, A. V., Trifonov, A. Yu.
core   +1 more source

New Late Cretaceous Paleomagnetic Results From the Eastern Qiangtang Terrane: Implications for the Postcollisional Extrusion and Convergence of the Southeastern Tibetan Plateau

open access: yesGeophysical Research Letters, Volume 51, Issue 22, 28 November 2024.
Abstract To refine the postcollisional extrusion and convergence history of the southeastern Tibetan Plateau, we report a quality paleomagnetic data set from Upper Cretaceous redbeds of the eastern Qiangtang Terrane (QT), where is situated at the front edge of eastern Himalayan Syntaxis.
Jiahui Ma   +10 more
wiley   +1 more source

Entangled Trajectories: The 2024 Electoral Year in Bulgaria and Romania

open access: yes
JCMS: Journal of Common Market Studies, Volume 63, Issue S1, Page 237-254, November 2025.
Sorina Soare   +2 more
wiley   +1 more source

Too Hot to Handle: A Meta‐Analytical Review of the Thermal Tolerance and Adaptive Capacity of North American Sturgeon

open access: yesGlobal Change Biology, Volume 30, Issue 11, November 2024.
Combining published data gathered from the field and in the laboratory, we examined how temperature impacts North American sturgeon to gauge how these threatened and endangered species will fare in an increasingly warming world. We found that, in response to prolonged warming, North American sturgeon can increase their upper thermal limit more so than ...
Angelina M. Dichiera   +4 more
wiley   +1 more source

The histone chaperones ASF1 and HIRA are required for telomere length and 45S rDNA copy number homeostasis

open access: yesThe Plant Journal, Volume 120, Issue 3, Page 1125-1141, November 2024.
Significance Statement The H3 histone chaperones ANTI‐SILENCING FUNCTION 1 (ASF1) and HISTONE REGULATOR A (HIRA) are crucial for telomere length homeostasis, 45S rRNA gene silencing, and determination of 45S rDNA copy number. ASF1 affects heterochromatin organization, and its function is linked to the telomere protective complex through possible ...
Adéla Machelová   +12 more
wiley   +1 more source

New HARPS and FEROS observations of GJ1046

open access: yes, 2018
In this paper we present new precise Doppler data of GJ1046 taken between November 2005 and July 2018 with the HARPS and the FEROS high-resolution spectographs.
Barragán, Oscar   +18 more
core  

A thermodynamic basis for prebiotic amino acid synthesis and the nature of the first genetic code

open access: yes, 2009
Of the twenty amino acids used in proteins, ten were formed in Miller's atmospheric discharge experiments. The two other major proposed sources of prebiotic amino acid synthesis include formation in hydrothermal vents and delivery to Earth via meteorites.
Chakrabarti S.   +2 more
core   +1 more source

VARIABILITY OF THE LEVEL OF INFLUENCE OF RED VOLE POPULATIONS BY HANTAVIRUS PUUMALA IN THE REPUBLIC OF TATARSTAN IN 2015–2017

open access: yesИнфекция и иммунитет, 2018
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T. A. Savitskaya   +11 more
doaj   +1 more source

Generation of Hidden Optical-Polarization: Squeezing and Non-Classicality

open access: yes, 2011
A monochromatic double-mode coherent light endowed with orthogonally polarized photons propagating collinearly is studied in Degenerate Parametric Amplification.
Agarwal   +36 more
core   +1 more source

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